Micro-and nanopatterned topographical cues for regulating macrophage cell shape and phenotype TU Luu, SC Gott, BWK Woo, MP Rao, WF Liu ACS applied materials & interfaces 7 (51), 28665-28672, 2015 | 293 | 2015 |
YAP-mediated mechanotransduction tunes the macrophage inflammatory response VS Meli, H Atcha, PK Veerasubramanian, RR Nagalla, TU Luu, EY Chen, ... Science advances 6 (49), eabb8471, 2020 | 158 | 2020 |
Mast cell and eosinophil activation are associated with COVID-19 and TLR-mediated viral inflammation: implications for an anti-Siglec-8 antibody S Gebremeskel, J Schanin, KM Coyle, M Butuci, T Luu, EC Brock, A Xu, ... Frontiers in immunology 12, 650331, 2021 | 107 | 2021 |
Topographical modulation of macrophage phenotype by shrink-film multi-scale wrinkles T Wang, TU Luu, A Chen, M Khine, WF Liu Biomaterials science 4 (6), 948-952, 2016 | 64 | 2016 |
Label-free identification of macrophage phenotype by fluorescence lifetime imaging microscopy A Alfonso-García, TD Smith, R Datta, TU Luu, E Gratton, EO Potma, ... Journal of biomedical optics 21 (4), 046005-046005, 2016 | 63 | 2016 |
Macrophage secretion heterogeneity in engineered microenvironments revealed using a microwell platform FY McWhorter, TD Smith, TU Luu, MK Rahim, JB Haun, WF Liu Integrative Biology 8 (7), 751-760, 2016 | 28 | 2016 |
Regulation of macrophages by extracellular matrix composition and adhesion geometry TU Luu, WF Liu Regenerative Engineering and Translational Medicine 4, 238-246, 2018 | 25 | 2018 |
The inhibitory receptor Siglec-8 interacts with FcεRI and globally inhibits intracellular signaling in primary mast cells upon activation W Korver, A Wong, S Gebremeskel, GL Negri, J Schanin, K Chang, ... Frontiers in Immunology 13, 833728, 2022 | 21 | 2022 |
Functional and phenotypic characterization of Siglec-6 on human mast cells PA Robida, CH Rische, NBB Morgenstern, R Janarthanam, Y Cao, ... Cells 11 (7), 1138, 2022 | 19 | 2022 |
A Src-H3 acetylation signaling axis integrates macrophage mechanosensation with inflammatory response PK Veerasubramanian, H Shao, VS Meli, TAQ Phan, TU Luu, WF Liu, ... Biomaterials 279, 121236, 2021 | 15 | 2021 |
Discovery of an agonistic Siglec-6 antibody that inhibits and reduces human mast cells J Schanin, W Korver, EC Brock, J Leung, Z Benet, T Luu, K Chang, A Xu, ... Communications Biology 5 (1), 1226, 2022 | 11 | 2022 |
Mast cell and eosinophil activation are associated with COVID-19 and TLR-mediated viral inflammation: implications for an anti-siglec-8 antibody. Front Immunol 2021; 12: 650331 S Gebremeskel, J Schanin, KM Coyle, M Butuci, T Luu, EC Brock, A Xu, ... DOI: https://doi. org/10.3389/fimmu, 650331, 2021 | 6 | 2021 |
An agonistic monoclonal antibody against Siglec-6 selectively inhibits and reduces human tissue mast cells J Schanin, T Luu, W Korver, EC Brock, Z Benet, A Xu, K Chang, A Wong, ... EAACI: Hamburg, Germany, 2022 | 3 | 2022 |
An agonistic monoclonal antibody against Siglec-6 broadly inhibits mast cell activation in transgenic mice Z Benet, T Luu, E Brock, R Sanchez, L McEwen, K Coyle, K Chang, ... Journal of Allergy and Clinical Immunology 151 (2), AB168, 2023 | 2 | 2023 |
Regulation of mast cells by overlapping but distinct protein interactions of Siglec‐6 and Siglec‐8 W Korver, Z Benet, A Wong, GL Negri, K Chang, R Sanchez, J Leung, ... Allergy, 2024 | 1 | 2024 |
Antibody Blockade of the Immunoinhibitory Receptor Siglec 10 Polarizes Tumor Associated Myeloid Cells and Promotes Anti-tumor Immunity J Schanin, M Peterson, T Luu, R Sanchez, LM McEwen, E Henneberry, ... BMJ Specialist Journals, 2022 | 1 | 2022 |
Anti-siglec-6 antibodies and methods of use thereof BA Youngblood, J Schanin, J Leung, W Korver, LUU Thuy, EC Brock US Patent App. 18/346,013, 2024 | | 2024 |
MRGPRX2-Mediated Mast Cell Activation is a Shared Pathogenic Mechanism in Atopic Dermatitis and Prurigo Nodularis Patients that can be Therapeutically Targeted via Siglecs Z Benet, T Luu, E Brock, R Sanchez, J Schanin, B Youngblood Journal of Allergy and Clinical Immunology 153 (2), AB62, 2024 | | 2024 |
Macro‐and micro‐scale culture environment differentially regulate the effects of crowding on macrophage function SCJ Hsu, TU Luu, TD Smith, WF Liu Biotechnology and Bioengineering 121 (1), 306-316, 2024 | | 2024 |
Global protein interactions of Siglec-6 and Siglec-8 reveal distinct differences in regulating mast cell function W Korver, Z Benet, A Wong, GL Negri, K Chang, J Leung, N De Freitas, ... ALLERGY 78, 212-213, 2023 | | 2023 |