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Thuy U. Luu
Thuy U. Luu
Ph.D in Pharmacological Sciences/Biomedical Engineering, University of California, Irvine
Dirección de correo verificada de uci.edu
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Micro-and nanopatterned topographical cues for regulating macrophage cell shape and phenotype
TU Luu, SC Gott, BWK Woo, MP Rao, WF Liu
ACS applied materials & interfaces 7 (51), 28665-28672, 2015
2932015
YAP-mediated mechanotransduction tunes the macrophage inflammatory response
VS Meli, H Atcha, PK Veerasubramanian, RR Nagalla, TU Luu, EY Chen, ...
Science advances 6 (49), eabb8471, 2020
1582020
Mast cell and eosinophil activation are associated with COVID-19 and TLR-mediated viral inflammation: implications for an anti-Siglec-8 antibody
S Gebremeskel, J Schanin, KM Coyle, M Butuci, T Luu, EC Brock, A Xu, ...
Frontiers in immunology 12, 650331, 2021
1072021
Topographical modulation of macrophage phenotype by shrink-film multi-scale wrinkles
T Wang, TU Luu, A Chen, M Khine, WF Liu
Biomaterials science 4 (6), 948-952, 2016
642016
Label-free identification of macrophage phenotype by fluorescence lifetime imaging microscopy
A Alfonso-García, TD Smith, R Datta, TU Luu, E Gratton, EO Potma, ...
Journal of biomedical optics 21 (4), 046005-046005, 2016
632016
Macrophage secretion heterogeneity in engineered microenvironments revealed using a microwell platform
FY McWhorter, TD Smith, TU Luu, MK Rahim, JB Haun, WF Liu
Integrative Biology 8 (7), 751-760, 2016
282016
Regulation of macrophages by extracellular matrix composition and adhesion geometry
TU Luu, WF Liu
Regenerative Engineering and Translational Medicine 4, 238-246, 2018
252018
The inhibitory receptor Siglec-8 interacts with FcεRI and globally inhibits intracellular signaling in primary mast cells upon activation
W Korver, A Wong, S Gebremeskel, GL Negri, J Schanin, K Chang, ...
Frontiers in Immunology 13, 833728, 2022
212022
Functional and phenotypic characterization of Siglec-6 on human mast cells
PA Robida, CH Rische, NBB Morgenstern, R Janarthanam, Y Cao, ...
Cells 11 (7), 1138, 2022
192022
A Src-H3 acetylation signaling axis integrates macrophage mechanosensation with inflammatory response
PK Veerasubramanian, H Shao, VS Meli, TAQ Phan, TU Luu, WF Liu, ...
Biomaterials 279, 121236, 2021
152021
Discovery of an agonistic Siglec-6 antibody that inhibits and reduces human mast cells
J Schanin, W Korver, EC Brock, J Leung, Z Benet, T Luu, K Chang, A Xu, ...
Communications Biology 5 (1), 1226, 2022
112022
Mast cell and eosinophil activation are associated with COVID-19 and TLR-mediated viral inflammation: implications for an anti-siglec-8 antibody. Front Immunol 2021; 12: 650331
S Gebremeskel, J Schanin, KM Coyle, M Butuci, T Luu, EC Brock, A Xu, ...
DOI: https://doi. org/10.3389/fimmu, 650331, 2021
62021
An agonistic monoclonal antibody against Siglec-6 selectively inhibits and reduces human tissue mast cells
J Schanin, T Luu, W Korver, EC Brock, Z Benet, A Xu, K Chang, A Wong, ...
EAACI: Hamburg, Germany, 2022
32022
An agonistic monoclonal antibody against Siglec-6 broadly inhibits mast cell activation in transgenic mice
Z Benet, T Luu, E Brock, R Sanchez, L McEwen, K Coyle, K Chang, ...
Journal of Allergy and Clinical Immunology 151 (2), AB168, 2023
22023
Regulation of mast cells by overlapping but distinct protein interactions of Siglec‐6 and Siglec‐8
W Korver, Z Benet, A Wong, GL Negri, K Chang, R Sanchez, J Leung, ...
Allergy, 2024
12024
Antibody Blockade of the Immunoinhibitory Receptor Siglec 10 Polarizes Tumor Associated Myeloid Cells and Promotes Anti-tumor Immunity
J Schanin, M Peterson, T Luu, R Sanchez, LM McEwen, E Henneberry, ...
BMJ Specialist Journals, 2022
12022
Anti-siglec-6 antibodies and methods of use thereof
BA Youngblood, J Schanin, J Leung, W Korver, LUU Thuy, EC Brock
US Patent App. 18/346,013, 2024
2024
MRGPRX2-Mediated Mast Cell Activation is a Shared Pathogenic Mechanism in Atopic Dermatitis and Prurigo Nodularis Patients that can be Therapeutically Targeted via Siglecs
Z Benet, T Luu, E Brock, R Sanchez, J Schanin, B Youngblood
Journal of Allergy and Clinical Immunology 153 (2), AB62, 2024
2024
Macro‐and micro‐scale culture environment differentially regulate the effects of crowding on macrophage function
SCJ Hsu, TU Luu, TD Smith, WF Liu
Biotechnology and Bioengineering 121 (1), 306-316, 2024
2024
Global protein interactions of Siglec-6 and Siglec-8 reveal distinct differences in regulating mast cell function
W Korver, Z Benet, A Wong, GL Negri, K Chang, J Leung, N De Freitas, ...
ALLERGY 78, 212-213, 2023
2023
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