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patrick j. pagano
patrick j. pagano
University of Pittsburgh
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Novel Competitive Inhibitor of NAD(P)H Oxidase Assembly Attenuates Vascular O2 and Systolic Blood Pressure in Mice
FE Rey, ME Cifuentes, A Kiarash, MT Quinn, PJ Pagano
Circulation research 89 (5), 408-414, 2001
7482001
Localization of a constitutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: Enhancement by angiotensin II
JK Clark, ME Cifuentes-Pagano
Proc Natl Acad Sci USA 94, 14438-14488, 1997
576*1997
Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling
I Al Ghouleh, NKH Khoo, UG Knaus, KK Griendling, RM Touyz, ...
Free Radical Biology and Medicine 51 (7), 1271-1288, 2011
2822011
Resveratrol induces prostate cancer cell entry into s phase and inhibits DNA synthesis
N Kuwajerwala, E Cifuentes, S Gautam, M Menon, ER Barrack, ...
Cancer Research 62 (9), 2488-2492, 2002
2502002
Upregulation of p67 phox and gp91 phox in aortas from angiotensin II-infused mice
ME Cifuentes, FE Rey, OA Carretero, PJ Pagano
American Journal of Physiology-Heart and Circulatory Physiology 279 (5 …, 2000
2182000
Proteolytic fragments of phosphoinositide-specific phospholipase C-delta 1. Catalytic and membrane binding properties
ME Cifuentes, L Honkanen, MJ Rebecchi
Journal of Biological Chemistry 268 (16), 11586-11593, 1993
2071993
Nox2 B-loop peptide, Nox2ds, specifically inhibits the NADPH oxidase Nox2
G Csányi, E Cifuentes-Pagano, I Al Ghouleh, DJ Ranayhossaini, L Egaña, ...
Free Radical Biology and Medicine 51 (6), 1116-1125, 2011
1432011
NADPH oxidase inhibitors: a decade of discovery from Nox2ds to HTS
E Cifuentes-Pagano, G Csanyi, PJ Pagano
Cellular and Molecular Life Sciences 69, 2315-2325, 2012
1142012
Targeting reactive oxygen species in hypertension
ME Cifuentes, PJ Pagano
Current opinion in nephrology and hypertension 15 (2), 179-186, 2006
1142006
Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging
AR Robinson, MJ Yousefzadeh, TA Rozgaja, J Wang, X Li, JS Tilstra, ...
Redox biology 17, 259-273, 2018
1122018
The quest for selective nox inhibitors and therapeutics: challenges, triumphs and pitfalls
E Cifuentes-Pagano, DN Meijles, PJ Pagano
Antioxidants & redox signaling 20 (17), 2741-2754, 2014
982014
Nox4 oxidase overexpression specifically decreases endogenous Nox4 mRNA and inhibits angiotensin II–induced adventitial myofibroblast migration
MJ Haurani, ME Cifuentes, AD Shepard, PJ Pagano
Hypertension 52 (1), 143-149, 2008
952008
Lack of glutathione peroxidase 1 accelerates cardiac-specific hypertrophy and dysfunction in angiotensin II hypertension
N Ardanaz, XP Yang, ME Cifuentes, MJ Haurani, KW Jackson, TD Liao, ...
Hypertension 55 (1), 116-123, 2010
802010
The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1
DN Meijles, S Sahoo, I Al Ghouleh, JH Amaral, R Bienes-Martinez, ...
Science signaling 10 (501), eaaj1784, 2017
732017
The role of NADPH oxidases in the etiology of obesity and metabolic syndrome: contribution of individual isoforms and cell biology
E DeVallance, Y Li, MJ Jurczak, E Cifuentes-Pagano, PJ Pagano
Antioxidants & Redox Signaling 31 (10), 687-709, 2019
662019
MEF2C-MYOCD and leiomodin1 suppression by miRNA-214 promotes smooth muscle cell phenotype switching in pulmonary arterial hypertension
S Sahoo, DN Meijles, I Al Ghouleh, M Tandon, E Cifuentes-Pagano, ...
PLoS One 11 (5), e0153780, 2016
642016
Selective inactivation of NADPH oxidase 2 causes regression of vascularization and the size and stability of atherosclerotic plaques
IM Quesada, A Lucero, C Amaya, DN Meijles, ME Cifuentes, PJ Pagano, ...
Atherosclerosis 242 (2), 469-475, 2015
522015
Synchronized prostate cancer cells for studying androgen regulated events in cell cycle progression from G1 into S phase
E Cifuentes, R Croxen, M Menon, ER Barrack, GPV Reddy
Journal of cellular physiology 195 (3), 337-345, 2003
462003
Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitors
E Cifuentes-Pagano, J Saha, G Csányi, I Al Ghouleh, S Sahoo, ...
Medchemcomm 4 (7), 1085-1092, 2013
422013
NADPH oxidase 2 inhibitors CPP11G and CPP11H attenuate endothelial cell inflammation & vessel dysfunction and restore mouse hind-limb flow
Y Li, E Cifuentes-Pagano, ER DeVallance, DS De Jesus, S Sahoo, ...
Redox biology 22, 101143, 2019
402019
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