Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin Diabetes Prevention Program Research Group New England Journal of Medicine 346 (6), 393-403, 2002 | 25846 | 2002 |
Mechanisms linking obesity to insulin resistance and type 2 diabetes SE Kahn, RL Hull, KM Utzschneider Nature 444 (7121), 840-846, 2006 | 6646 | 2006 |
Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy SE Kahn, SM Haffner, MA Heise, WH Herman, RR Holman, NP Jones, ... New England Journal of Medicine 355 (23), 2427-2443, 2006 | 4169 | 2006 |
10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study Diabetes Prevention Program Research Group The Lancet 374 (9702), 1677-1686, 2009 | 3662 | 2009 |
Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes Look AHEAD Research Group New England Journal of Medicine 369 (2), 145-154, 2013 | 3146 | 2013 |
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes SE Kahn Diabetologia 46, 3-19, 2003 | 2944 | 2003 |
Pathophysiology and treatment of type 2 diabetes: perspectives on the past, present, and future SE Kahn, ME Cooper, S Del Prato The Lancet 383 (9922), 1068-1083, 2014 | 2273 | 2014 |
The Diabetes Prevention Program (DPP): description of lifestyle intervention Diabetes Prevention Program Research Group Diabetes Care 25 (12), 2165-2171, 2002 | 2090 | 2002 |
Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex M Cnop, PJ Havel, KM Utzschneider, DB Carr, MK Sinha, EJ Boyko, ... Diabetologia 46, 459-469, 2003 | 2059 | 2003 |
Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the Look AHEAD trial Look AHEAD Research Group Diabetes Care 30 (6), 1374-1383, 2007 | 2035 | 2007 |
Quantification of the relationship between insulin sensitivity and β-cell function in human subjects: evidence for a hyperbolic function SE Kahn, RL Prigeon, DK McCulloch, EJ Boyko, RN Bergman, ... Diabetes 42 (11), 1663-1672, 1993 | 1938 | 1993 |
Effect of weight loss with lifestyle intervention on risk of diabetes RF Hamman, RR Wing, SL Edelstein, JM Lachin, GA Bray, L Delahanty, ... Diabetes Care 29 (9), 2102-2107, 2006 | 1693 | 2006 |
Long term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes: four year results of the Look AHEAD trial Look AHEAD Research Group Archives of Internal Medicine 170 (17), 1566-1575, 2010 | 1666 | 2010 |
Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity UB Pajvani, M Hawkins, TP Combs, MW Rajala, T Doebber, JP Berger, ... Journal of Biological Chemistry 279 (13), 12152-12162, 2004 | 1505 | 2004 |
Intra-abdominal fat is a major determinant of the National Cholesterol Education Program Adult Treatment Panel III criteria for the metabolic syndrome DB Carr, KM Utzschneider, RL Hull, K Kodama, BM Retzlaff, JD Brunzell, ... Diabetes 53 (8), 2087-2094, 2004 | 1492 | 2004 |
Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes SL Masters, A Dunne, SL Subramanian, RL Hull, GM Tannahill, FA Sharp, ... Nature Immunology 11 (10), 897-904, 2010 | 1452 | 2010 |
The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial TJ Orchard, M Temprosa, R Goldberg, S Haffner, R Ratner, S Marcovina, ... Annals of Internal Medicine 142 (8), 611-619, 2005 | 1313 | 2005 |
Effect of linagliptin vs placebo on major cardiovascular events in adults with type 2 diabetes and high cardiovascular and renal risk: the CARMELINA randomized clinical trial J Rosenstock, V Perkovic, OE Johansen, ME Cooper, SE Kahn, N Marx, ... JAMA 321 (1), 69-79, 2019 | 1159 | 2019 |
Glucose levels and risk of dementia PK Crane, R Walker, RA Hubbard, G Li, DM Nathan, H Zheng, S Haneuse, ... New England Journal of Medicine 369 (6), 540-548, 2013 | 1115 | 2013 |
The role of insulin resistance in nonalcoholic fatty liver disease KM Utzschneider, SE Kahn The Journal of Clinical Endocrinology & Metabolism 91 (12), 4753-4761, 2006 | 1106 | 2006 |