Qi Chen
Qi Chen
University of Kansas Medial Center
Dirección de correo verificada de kumc.edu
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Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...
Autophagy 12 (1), 1-222, 2016
8737*2016
Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues
Q Chen, MG Espey, MC Krishna, JB Mitchell, CP Corpe, GR Buettner, ...
Proceedings of the National Academy of Sciences 102 (38), 13604-13609, 2005
9352005
Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice
Q Chen, MG Espey, AY Sun, C Pooput, KL Kirk, MC Krishna, DB Khosh, ...
Proceedings of the National Academy of Sciences 105 (32), 11105-11109, 2008
7362008
Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo
Q Chen, MG Espey, AY Sun, JH Lee, MC Krishna, E Shacter, PL Choyke, ...
Proceedings of the National Academy of Sciences 104 (21), 8749-8754, 2007
5892007
High-dose parenteral ascorbate enhanced chemosensitivity of ovarian cancer and reduced toxicity of chemotherapy
Y Ma, J Chapman, M Levine, K Polireddy, J Drisko, Q Chen
Science translational medicine 6 (222), 222ra18-222ra18, 2014
2832014
Vitamin C: intravenous use by complementary and alternative medicine practitioners and adverse effects
SJ Padayatty, AY Sun, Q Chen, MG Espey, J Drisko, M Levine
PloS one 5 (7), e11414, 2010
2832010
Synthesis, acute toxicities, and antitumor effects of novel 9-substituted β-carboline derivatives
R Cao, Q Chen, X Hou, H Chen, H Guan, Y Ma, W Peng, A Xu
Bioorganic & medicinal chemistry 12 (17), 4613-4623, 2004
1862004
Antitumor and neurotoxic effects of novel harmine derivatives and structure‐activity relationship analysis
Q Chen, R Chao, H Chen, X Hou, H Yan, S Zhou, W Peng, A Xu
International Journal of Cancer 114 (5), 675-682, 2005
1492005
Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer
MG Espey, P Chen, B Chalmers, J Drisko, AY Sun, M Levine, Q Chen
Free Radical Biology and Medicine 50 (11), 1610-1619, 2011
1442011
Pharmacological ascorbate induces cytotoxicity in prostate cancer cells through ATP depletion and induction of autophagy
P Chen, J Yu, B Chalmers, J Drisko, J Yang, B Li, Q Chen
Anti-cancer drugs 23 (4), 437-444, 2012
842012
Synthesis and in vitro cytotoxic evaluation of 1, 3-bisubstituted and 1, 3, 9-trisubstituted β-carboline derivatives
R Cao, W Peng, H Chen, X Hou, H Guan, Q Chen, Y Ma, A Xu
European journal of medicinal chemistry 40 (3), 249-257, 2005
782005
Losing and finding a way at C: new promise for pharmacologic ascorbate in cancer treatment
M Levine, MG Espey, Q Chen
Free radical biology & medicine 47 (1), 27, 2009
682009
Anti-cancer effect of pharmacologic ascorbate and its interaction with supplementary parenteral glutathione in preclinical cancer models
P Chen, J Stone, G Sullivan, JA Drisko, Q Chen
Free Radical Biology and Medicine 51 (3), 681-687, 2011
532011
Cancer of the pancreas: molecular pathways and current advancement in treatment
K Polireddy, Q Chen
Journal of Cancer 7 (11), 1497, 2016
512016
Antitumor activities of Rauwolfia vomitoria extract and potentiation of carboplatin effects against ovarian cancer
J Yu, Y Ma, J Drisko, Q Chen
Current Therapeutic Research 75, 8-14, 2013
512013
High dose parenteral ascorbate inhibited pancreatic cancer growth and metastasis: mechanisms and a phase I/IIa study
K Polireddy, R Dong, G Reed, J Yu, P Chen, S Williamson, PC Violet, ...
Scientific reports 7 (1), 1-15, 2017
452017
Apoptosis of a human non-small cell lung cancer (NSCLC) cell line, PLA-801, induced by acutiaporberine, a novel bisalkaloid derived from Thalictrum acutifolium (Hand.-Mazz.) Boivin
Q Chen, W Peng, A Xu
Biochemical pharmacology 63 (8), 1389-1396, 2002
412002
Apoptosis of human highly metastatic lung cancer cell line 95-D induced by acutiaporberine, a novel bisalkaloid derived from Thalictrum acutifolium
Q Chen, W Peng, S Qi, A Xu
Planta Medica 68 (06), 550-553, 2002
322002
Mechanism of ascorbate-induced cell death in human pancreatic cancer cells: Role of Bcl-2, Beclin 1 and autophagy
M Fukui, N Yamabe, HJ Choi, K Polireddy, Q Chen, BT Zhu
Planta medica 81 (10), 838-846, 2015
292015
Syntheses, Crystal Structures and Cytotoxities of Silver (I) Complexes of 2, 2′‐Bipyridines and 1, 10‐Phenanthroline
HL Zhu, Q Chen, WL Peng, SJ Qi, AL Xu, XM Chen
Chinese Journal of Chemistry 19 (3), 263-267, 2001
292001
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Artículos 1–20