Neuropathology of Alzheimer's disease DP Perl Mount Sinai Journal of Medicine: A Journal of Translational and Personalized …, 2010 | 1218 | 2010 |
A patient-derived glioblastoma organoid model and biobank recapitulates inter-and intra-tumoral heterogeneity F Jacob, RD Salinas, DY Zhang, PTT Nguyen, JG Schnoll, SZH Wong, ... Cell 180 (1), 188-204. e22, 2020 | 642 | 2020 |
Functional impairment of microglia coincides with Beta-amyloid deposition in mice with Alzheimer-like pathology G Krabbe, A Halle, V Matyash, JL Rinnenthal, GD Eom, U Bernhardt, ... PloS one 8 (4), e60921, 2013 | 535 | 2013 |
Formation and maintenance of Alzheimer's disease β-amyloid plaques in the absence of microglia SA Grathwohl, RE Kälin, T Bolmont, S Prokop, G Winkelmann, SA Kaeser, ... Nature neuroscience 12 (11), 1361-1363, 2009 | 493 | 2009 |
Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease–like pathology and cognitive decline J Vom Berg, S Prokop, KR Miller, J Obst, RE Kälin, I Lopategui-Cabezas, ... Nature medicine 18 (12), 1812-1819, 2012 | 471 | 2012 |
PEN-2 is an integral component of the γ-secretase complex required for coordinated expression of presenilin and nicastrin H Steiner, E Winkler, D Edbauer, S Prokop, G Basset, A Yamasaki, ... Journal of Biological Chemistry 277 (42), 39062-39065, 2002 | 423 | 2002 |
Novel Pentameric Thiophene Derivatives for in Vitro and in Vivo Optical Imaging of a Plethora of Protein Aggregates in Cerebral Amyloidoses A Åslund, CJ Sigurdson, T Klingstedt, S Grathwohl, T Bolmont, ... ACS chemical biology 4 (8), 673-684, 2009 | 367 | 2009 |
Microglia actions in Alzheimer’s disease S Prokop, KR Miller, FL Heppner Acta neuropathologica 126, 461-477, 2013 | 335 | 2013 |
Identification of distinct γ-secretase complexes with different APH-1 variants K Shirotani, D Edbauer, S Prokop, C Haass, H Steiner Journal of Biological Chemistry 279 (40), 41340-41345, 2004 | 231 | 2004 |
High-fat diet-induced brain region-specific phenotypic spectrum of CNS resident microglia C Baufeld, A Osterloh, S Prokop, KR Miller, FL Heppner Acta neuropathologica 132, 361-375, 2016 | 217 | 2016 |
Requirement of PEN-2 for stabilization of the presenilin N-/C-terminal fragment heterodimer within the γ-secretase complex S Prokop, K Shirotani, D Edbauer, C Haass, H Steiner Journal of Biological Chemistry 279 (22), 23255-23261, 2004 | 196 | 2004 |
γ-Secretase complex assembly within the early secretory pathway A Capell, D Beher, S Prokop, H Steiner, C Kaether, MS Shearman, ... Journal of Biological Chemistry 280 (8), 6471-6478, 2005 | 131 | 2005 |
Evidence for Age-Dependent in Vivo Conformational Rearrangement within Aβ Amyloid Deposits S Nyström, KM Psonka-Antonczyk, PG Ellingsen, LBG Johansson, ... ACS chemical biology 8 (6), 1128-1133, 2013 | 120 | 2013 |
Impact of peripheral myeloid cells on amyloid-β pathology in Alzheimer’s disease–like mice S Prokop, KR Miller, N Drost, S Handrick, V Mathur, J Luo, A Wegner, ... Journal of Experimental Medicine 212 (11), 1811-1818, 2015 | 114 | 2015 |
“Don’t Phos Over Tau”: recent developments in clinical biomarkers and therapies targeting tau phosphorylation in Alzheimer’s disease and other tauopathies Y Xia, S Prokop, BI Giasson Molecular neurodegeneration 16 (1), 37, 2021 | 111 | 2021 |
Impairment of immunoproteasome function by β5i/LMP7 subunit deficiency results in severe enterovirus myocarditis E Opitz, A Koch, K Klingel, F Schmidt, S Prokop, A Rahnefeld, M Sauter, ... PLoS pathogens 7 (9), e1002233, 2011 | 111 | 2011 |
M2 polarized macrophages and giant cells contribute to myofibrosis in neuromuscular sarcoidosis S Prokop, FL Heppner, HH Goebel, W Stenzel The American journal of pathology 178 (3), 1279-1286, 2011 | 109 | 2011 |
Nuclear Translocation Uncovers the Amyloid Peptide Aβ42 as a Regulator of Gene Transcription*♦ C Barucker, A Harmeier, J Weiske, B Fauler, KF Albring, S Prokop, ... Journal of Biological Chemistry 289 (29), 20182-20191, 2014 | 87 | 2014 |
Impact of TREM2 risk variants on brain region-specific immune activation and plaque microenvironment in Alzheimer’s disease patient brain samples S Prokop, KR Miller, SR Labra, RM Pitkin, K Hoxha, S Narasimhan, ... Acta neuropathologica 138, 613-630, 2019 | 74 | 2019 |
Tau Ser208 phosphorylation promotes aggregation and reveals neuropathologic diversity in Alzheimer’s disease and other tauopathies Y Xia, S Prokop, KMM Gorion, JD Kim, ZA Sorrentino, BM Bell, ... Acta Neuropathologica Communications 8, 1-17, 2020 | 68 | 2020 |