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Katarina Spilovska
Katarina Spilovska
Univerzity of Hradec Kralove
Dirección de correo verificada de uhk.cz
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Adamantane–a lead structure for drugs in clinical practice
K Spilovska, F Zemek, J Korabecny, E Nepovimova, O Soukup, ...
Current medicinal chemistry 23 (29), 3245-3266, 2016
1842016
Synthesis and biological evaluation of novel tacrine derivatives and tacrine–coumarin hybrids as cholinesterase inhibitors
S Hamulakova, L Janovec, M Hrabinova, K Spilovska, J Korabecny, ...
Journal of medicinal chemistry 57 (16), 7073-7084, 2014
1212014
7-MEOTA–donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies
J Korabecny, R Dolezal, P Cabelova, A Horova, E Hruba, J Ricny, ...
European journal of medicinal chemistry 82, 426-438, 2014
942014
7-Methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors in Alzheimer’s disease treatment—synthesis, biological evaluation and molecular modeling studies
K Spilovska, J Korabecny, J Kral, A Horova, K Musilek, O Soukup, ...
Molecules 18 (2), 2397-2418, 2013
922013
Multitarget Tacrine Hybrids with Neuroprotective Properties to Confront Alzheimer’s Disease
K Spilovska, J Korabecny, E Nepovimova, R Dolezal, E Mezeiova, ...
Current topics in medicinal chemistry 17 (9), 1006-1026, 2017
892017
From pyridinium-based to centrally active acetylcholinesterase reactivators
J Korabecny, O Soukup, R Dolezal, K Spilovska, E Nepovimova, M Andrs, ...
Mini reviews in medicinal chemistry 14 (3), 215-221, 2014
682014
Novel Tacrine-Scutellarin Hybrids as Multipotent Anti-Alzheimer’s Agents: Design, Synthesis and Biological Evaluation
K Spilovska, J Korabecny, V Sepsova, D Jun, M Hrabinova, P Jost, ...
Molecules 22 (6), 1006, 2017
502017
Multi-target-directed therapeutic potential of 7-methoxytacrine-adamantylamine heterodimers in the Alzheimer's disease treatment
Z Gazova, O Soukup, V Sepsova, K Siposova, L Drtinova, P Jost, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (2), 607-619, 2017
492017
Design, synthesis and in vitro testing of 7-methoxytacrine-amantadine analogues: A novel cholinesterase inhibitors for the treatment of Alzheimer’s disease
K Spilovska, J Korabecny, A Horova, K Musilek, E Nepovimova, ...
Medicinal Chemistry Research 24 (6), 2645-2655, 2015
402015
Development of 2-Methoxyhuprine as Novel Lead for Alzheimer’s Disease Therapy
E Mezeiova, J Korabecny, V Sepsova, M Hrabinova, P Jost, L Muckova, ...
Molecules 22 (8), 1265, 2017
332017
Tacrine and its derivatives in the therapy of Alzheimers disease
J Korábečný, K Spilovska, O Benek, K Musilek, O Soukup, K Kuča
Ceska a Slovenska farmacie: casopis Ceske farmaceuticke spolecnosti a …, 2012
122012
Intended pharmacotherapeutical approaches of Alzheimer's disease therapy
J Korábecný, E Hruba, O Soukup, F Zemek, K Musilek, E Nepovimova, ...
Ceska a Slovenska farmacie: casopis Ceske farmaceuticke spolecnosti a …, 2012
42012
Development of multi-target drugs for Alzheimer's disease based on acetylcholinesterasse inhibitors
J Korabecny, O Soukup, J Ricny, K Spilovska, E Nepovimova, K Kuca
JOURNAL OF NEUROCHEMISTRY 142, 213-213, 2017
2017
Alzheimer's Disease Drugs-In Vitro Comparison of Cholinesterase Inhibition and beta-amyloid Modulation
O Holas, J Korabecny, Z Gazova, K Siposova, K Musilek, V Opletalova, ...
Letters in Drug Design & Discovery 14 (6), 743-750, 2017
2017
Anti-amyloid activity of 7-MEOTA-Adamantylamine Heterodimers in the treatment of Alzheimert's disease
K Siposova, O Soukup, V Sepsova, L Drtinova, K Spilovska, K Kuca, ...
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 44, S105-S105, 2015
2015
Interaction of 7-Methoxytacrine-Adamantylamine Cholinesterase Inhibitors with Nicotinic and Muscarinic Acetylcholine Receptors
ZJ Wang, V Sepsova, K Spilovska, TS Mohamed, AK Hamouda
Biophysical Journal 108 (2), 430a, 2015
2015
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