Professor of Molecular Pharmacology, Glasgow University
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DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling
JK Millar, BS Pickard, S Mackie, R James, S Christie, SR Buchanan, ...
Science 310 (5751), 1187-1191, 2005
Targeting of cyclic AMP degradation to β2-adrenergic receptors by β-arrestins
SJ Perry, GS Baillie, TA Kohout, I McPhee, MM Magiera, KL Ang, ...
Science 298 (5594), 834-836, 2002
Matrix polymers of Candida biofilms and their possible role in biofilm resistance to antifungal agents
GS Baillie, LJ Douglas
Journal of Antimicrobial Chemotherapy 46 (3), 397-403, 2000
Sleep deprivation impairs cAMP signalling in the hippocampus
CG Vecsey, GS Baillie, D Jaganath, R Havekes, A Daniels, M Wimmer, ...
Nature 461 (7267), 1122-1125, 2009
Mixed species biofilms of Candida albicans and Staphylococcus epidermidis
B Adam, GS Baillie, LJ Douglas
Journal of medical microbiology 51 (4), 344-349, 2002
Apremilast, a cAMP phosphodiesterase‐4 inhibitor, demonstrates anti‐inflammatory activity in vitro and in a model of psoriasis
PH Schafer, A Parton, AK Gandhi, L Capone, M Adams, L Wu, JB Bartlett, ...
British journal of pharmacology 159 (4), 842-855, 2010
β-Arrestin-mediated PDE4 cAMP phosphodiesterase recruitment regulates β-adrenoceptor switching from Gs to Gi
GS Baillie, A Sood, I McPhee, I Gall, SJ Perry, RJ Lefkowitz, MD Houslay
Proceedings of the National Academy of Sciences 100 (3), 940-945, 2003
Role of dimorphism in the development of Candida albicans biofilms
GS Baillie, LJ Douglas
Journal of medical microbiology 48 (7), 671-679, 1999
cAMP-Specific phosphodiesterase-4 enzymes in the cardiovascular system: a molecular toolbox for generating compartmentalized cAMP signaling
MD Houslay, GS Baillie, DH Maurice
Circulation research 100 (7), 950-966, 2007
Effect of Growth Rate on Resistance ofCandida albicans Biofilms to Antifungal Agents
GS Baillie, LJ Douglas
Antimicrobial agents and chemotherapy 42 (8), 1900-1905, 1998
The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579
R Hoffmann, GS Baillie, SJ MacKenzie, SJ Yarwood, MD Houslay
The EMBO journal 18 (4), 893-903, 1999
Long PDE4 cAMP specific phosphodiesterases are activated by protein kinase A-mediated phosphorylation of a single serine residue in Upstream Conserved Region 1 (UCR1)
SJ MacKenzie, GS Baillie, I McPhee, C MacKenzie, R Seamons, ...
British journal of pharmacology 136 (3), 421, 2002
ERK2 mitogen-activated protein kinase binding, phosphorylation, and regulation of the PDE4D cAMP-specific phosphodiesterases: the involvement of COOH-terminal docking sites and …
SJ MacKenzie, GS Baillie, I McPhee, GB Bolger, MD Houslay
Journal of Biological Chemistry 275 (22), 16609-16617, 2000
Compartmentalized signalling: spatial regulation of cAMP by the action of compartmentalized phosphodiesterases
GS Baillie
The FEBS journal 276 (7), 1790-1799, 2009
Compartmentalisation of phosphodiesterases and protein kinase A: opposites attract
GS Baillie, JD Scott, MD Houslay
FEBS letters 579 (15), 3264-3270, 2005
RNA silencing identifies PDE4D5 as the functionally relevant cAMP phosphodiesterase interacting with βarrestin to control the protein kinase A/AKAP79-mediated switching of the …
MJ Lynch, GS Baillie, A Mohamed, X Li, C Maisonneuve, E Klussmann, ...
Journal of Biological Chemistry 280 (39), 33178-33189, 2005
Protein kinase A type I and type II define distinct intracellular signaling compartments
G Di Benedetto, A Zoccarato, V Lissandron, A Terrin, X Li, MD Houslay, ...
Circulation research 103 (8), 836-844, 2008
Therapeutic targeting of 3′, 5′-cyclic nucleotide phosphodiesterases: inhibition and beyond
GS Baillie, GS Tejeda, MP Kelly
Nature reviews Drug discovery 18 (10), 770-796, 2019
Sleep deprivation causes memory deficits by negatively impacting neuronal connectivity in hippocampal area CA1
R Havekes, AJ Park, JC Tudor, VG Luczak, RT Hansen, SL Ferri, ...
Elife 5, e13424, 2016
Production of extracellular matrix by Candida albicans biofilms
SP Hawser, GS Baillie, LJ Douglas
Journal of medical microbiology 47 (3), 253-256, 1998
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