Guy Berchem MD, PhD
Guy Berchem MD, PhD
Medical Oncologist CHL and Ass. Medical Director Luxembourg Institute of Health
Verified email at
Cited by
Cited by
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
First-Line Crizotinib versus Chemotherapy in ALK-Positive Lung Cancer
BJ Solomon, T Mok, DW Kim, YL Wu, K Nakagawa, T Mekhail, E Felip, ...
New England Journal of Medicine 371 (23), 2167-2177, 2014
Cetuximab plus chemotherapy in patients with advanced non-small-cell lung cancer (FLEX): an open-label randomised phase III trial
R Pirker, JR Pereira, A Szczesna, J von Pawel, M Krzakowski, R Ramlau, ...
The Lancet 373 (9674), 1525-1531, 2009
Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts
J Paggetti, F Haderk, M Seiffert, B Janji, U Distler, W Ammerlaan, YJ Kim, ...
Blood, The Journal of the American Society of Hematology 126 (9), 1106-1117, 2015
Cathepsin-D affects multiple tumor progression steps in vivo: proliferation, angiogenesis and apoptosis
G Berchem, M Glondu, M Gleizes, JP Brouillet, F Vignon, M Garcia, ...
Oncogene 21 (38), 5951-5955, 2002
A secreted FGF-binding protein can serve as the angiogenic switch in human cancer
F Czubayko, EDE Liaudet-Coopman, A Aigner, AT Tuveson, GJ Berchem, ...
Nature medicine 3 (10), 1137-1140, 1997
Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia
J Baginska, E Viry, G Berchem, A Poli, MZ Noman, K van Moer, S Medves, ...
Proceedings of the National Academy of Sciences 110 (43), 17450-17455, 2013
Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer
G Berchem, MZ Noman, M Bosseler, J Paggetti, S Baconnais, E Le Cam, ...
Oncoimmunology 5 (4), e1062968, 2016
Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression
MZ Noman, B Janji, B Kaminska, K Van Moer, S Pierson, P Przanowski, ...
Cancer research 71 (18), 5976-5986, 2011
MicroRNA as biomarkers and regulators in B-cell chronic lymphocytic leukemia
E Moussay, K Wang, JH Cho, K van Moer, S Pierson, J Paggetti, ...
Proceedings of the National Academy of Sciences 108 (16), 6573-6578, 2011
Melanoma angiogenesis and metastasis modulated by ribozyme targeting of the secreted growth factor pleiotrophin
F Czubayko, AM Schulte, GJ Berchem, A Wellstein
Proceedings of the National Academy of Sciences 93 (25), 14753-14758, 1996
The critical role of the tumor microenvironment in shaping natural killer cell-mediated anti-tumor immunity
J Baginska, E Viry, J Paggetti, S Medves, G Berchem, E Moussay, B Janji
Frontiers in immunology 4, 73994, 2013
Androgens Induce Resistance to bcl-2-mediated Apoptosis in LNCaP Prostate Cancer Cells
GJ Berchem, M Bosseler, LVY Sugars, H James Voeller, S Zeitlin, ...
Cancer research 55 (4), 735-738, 1995
Challenges with advanced therapy medicinal products and how to meet them
Nature reviews Drug discovery 9 (3), 195-201, 2010
Targeting autophagy inhibits melanoma growth by enhancing NK cells infiltration in a CCL5-dependent manner
T Mgrditchian, T Arakelian, J Paggetti, MZ Noman, E Viry, E Moussay, ...
Proceedings of the National Academy of Sciences 114 (44), E9271-E9279, 2017
Assessing cellular and circulating miRNA recovery: the impact of the RNA isolation method and the quantity of input material
V El-Khoury, S Pierson, T Kaoma, F Bernardin, G Berchem
Scientific reports 6 (1), 19529, 2016
Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti–PD-1/PD-L1 immunotherapy
MZ Noman, S Parpal, K Van Moer, M Xiao, Y Yu, T Arakelian, J Viklund, ...
Science advances 6 (18), eaax7881, 2020
Improving cancer immunotherapy by targeting the hypoxic tumor microenvironment: new opportunities and challenges
MZ Noman, M Hasmim, A Lequeux, M Xiao, C Duhem, S Chouaib, ...
Cells 8 (9), 1083, 2019
The acquisition of resistance to TNFα in breast cancer cells is associated with constitutive activation of autophagy as revealed by a transcriptome analysis using a custom …
E Moussay, T Kaoma, J Baginska, A Muller, K Van Moer, N Nicot, ...
Autophagy 7 (7), 760-770, 2011
Dual PD1/LAG3 immune checkpoint blockade limits tumor development in a murine model of chronic lymphocytic leukemia
M Wierz, S Pierson, L Guyonnet, E Viry, A Lequeux, A Oudin, SP Niclou, ...
Blood, The Journal of the American Society of Hematology 131 (14), 1617-1621, 2018
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