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Giorgio Tarzia
Giorgio Tarzia
Honorary Professor, Medicinal Chemistry, University of Urbino
Dirección de correo verificada de uniurb.it
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Modulation of anxiety through blockade of anandamide hydrolysis
S Kathuria, S Gaetani, D Fegley, F Valiño, A Duranti, A Tontini, M Mor, ...
Nature medicine 9 (1), 76-81, 2003
16532003
Oleylethanolamide regulates feeding and body weight through activation of the nuclear receptor PPAR-α
J Fu, S Gaetani, F Oveisi, J Lo Verme, A Serrano, ...
Nature 425 (6953), 90-93, 2003
12762003
An endocannabinoid mechanism for stress-induced analgesia
AG Hohmann, RL Suplita, NM Bolton, MH Neely, D Fegley, R Mangieri, ...
Nature 435 (7045), 1108-1112, 2005
8692005
Antidepressant-like activity and modulation of brain monoaminergic transmission by blockade of anandamide hydrolysis
G Gobbi, FR Bambico, R Mangieri, M Bortolato, P Campolongo, M Solinas, ...
Proceedings of the National Academy of Sciences 102 (51), 18620-18625, 2005
7742005
Characterization of the fatty acid amide hydrolase inhibitor cyclohexyl carbamic acid 3′-carbamoyl-biphenyl-3-yl ester (URB597): effects on anandamide and oleoylethanolamide …
D Fegley, S Gaetani, A Duranti, A Tontini, M Mor, G Tarzia, D Piomelli
Journal of Pharmacology and Experimental Therapeutics 313 (1), 352-358, 2005
4772005
Pharmacological profile of the selective FAAH inhibitor KDS‐4103 (URB597)
D Piomelli, G Tarzia, A Duranti, A Tontini, M Mor, TR Compton, O Dasse, ...
CNS drug reviews 12 (1), 21-38, 2006
4332006
Antidepressant-like activity of the fatty acid amide hydrolase inhibitor URB597 in a rat model of chronic mild stress
M Bortolato, RA Mangieri, J Fu, JH Kim, O Arguello, A Duranti, A Tontini, ...
Biological psychiatry 62 (10), 1103-1110, 2007
3942007
Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism
JR Clapper, G Moreno-Sanz, R Russo, A Guijarro, F Vacondio, A Duranti, ...
Nature neuroscience 13 (10), 1265-1270, 2010
3742010
Cyclohexylcarbamic acid 3 ‘-or 4 ‘-substituted biphenyl-3-yl esters as fatty acid amide hydrolase inhibitors: synthesis, quantitative structure− activity relationships, and …
M Mor, S Rivara, A Lodola, PV Plazzi, G Tarzia, A Duranti, A Tontini, ...
Journal of medicinal chemistry 47 (21), 4998-5008, 2004
3272004
Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus
JK Makara, M Mor, D Fegley, SI Szabó, S Kathuria, G Astarita, A Duranti, ...
Nature neuroscience 8 (9), 1139-1141, 2005
2652005
Selective N-acylethanolamine-hydrolyzing acid amidase inhibition reveals a key role for endogenous palmitoylethanolamide in inflammation
C Solorzano, C Zhu, N Battista, G Astarita, A Lodola, S Rivara, M Mor, ...
Proceedings of the National Academy of Sciences 106 (49), 20966-20971, 2009
2632009
The fatty acid amide hydrolase inhibitor URB597 (cyclohexylcarbamic acid 3′-carbamoylbiphenyl-3-yl ester) reduces neuropathic pain after oral administration in mice
R Russo, J LoVerme, G La Rana, TR Compton, J Parrott, A Duranti, ...
Journal of Pharmacology and Experimental Therapeutics 322 (1), 236-242, 2007
2102007
Design, synthesis, and structure− activity relationships of alkylcarbamic acid aryl esters, a new class of fatty acid amide hydrolase inhibitors
G Tarzia, A Duranti, A Tontini, G Piersanti, M Mor, S Rivara, PV Plazzi, ...
Journal of medicinal chemistry 46 (12), 2352-2360, 2003
2072003
Synthesis, antimicrobial activity and binding properties of calix [4] arene based vancomycin mimics
A Casnati, M Fabbi, N Pelizzi, A Pochini, F Sansone, R Unguro, ...
Bioorganic & Medicinal Chemistry Letters 6 (22), 2699-2704, 1996
1681996
Promotion of non-rapid eye movement sleep and activation of reticular thalamic neurons by a novel MT2 melatonin receptor ligand
R Ochoa-Sanchez, S Comai, B Lacoste, FR Bambico, ...
Journal of Neuroscience 31 (50), 18439-18452, 2011
1422011
Synthesis and characterization of a peripherally restricted CB1 cannabinoid antagonist, URB447, that reduces feeding and body-weight gain in mice
J LoVerme, A Duranti, A Tontini, G Spadoni, M Mor, S Rivara, N Stella, ...
Bioorganic & medicinal chemistry letters 19 (3), 639-643, 2009
1302009
2-[N-Acylamino(C1−C3)alkyl]indoles as MT1 Melatonin Receptor Partial Agonists, Antagonists, and Putative Inverse Agonists
G Spadoni, C Balsamini, A Bedini, G Diamantini, B Di Giacomo, A Tontini, ...
Journal of medicinal chemistry 41 (19), 3624-3634, 1998
1301998
Plant-derived phenolic compounds prevent the DNA single-strand breakage and cytotoxicity induced by tert-butylhydroperoxide via an iron-chelating mechanism
P Sestili, G Diamantini, A Bedini, L Cerioni, I Tommasini, G Tarzia, ...
Biochemical Journal 364 (1), 121-128, 2002
1292002
URB602 inhibits monoacylglycerol lipase and selectively blocks 2-arachidonoylglycerol degradation in intact brain slices
AR King, A Duranti, A Tontini, S Rivara, A Rosengarth, JR Clapper, ...
Chemistry & biology 14 (12), 1357-1365, 2007
1252007
Endocannabinoids in the treatment of mood disorders: evidence from animal models
F Rodriguez Bambico, A Duranti, A Tontini, G Tarzia, G Gobbi
Current Pharmaceutical Design 15 (14), 1623-1646, 2009
1152009
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20