An integrated physico-chemical approach for explaining the differential impact of FLASH versus conventional dose rate irradiation on cancer and normal tissue responses DR Spitz, GR Buettner, MS Petronek, JJ St-Aubin, RT Flynn, TJ Waldron, ... Radiotherapy and oncology 139, 23-27, 2019 | 300 | 2019 |
Linking cancer metabolic dysfunction and genetic instability through the lens of iron metabolism MS Petronek, DR Spitz, GR Buettner, BG Allen Cancers 11 (8), 1077, 2019 | 57 | 2019 |
Combination therapy with radiation and PARP inhibition enhances responsiveness to anti-PD-1 therapy in colorectal tumor models SN Seyedin, MM Hasibuzzaman, V Pham, MS Petronek, C Callaghan, ... International Journal of Radiation Oncology* Biology* Physics 108 (1), 81-92, 2020 | 41 | 2020 |
Elucidating the neurological mechanism of the FLASH effect in juvenile mice exposed to hypofractionated radiotherapy BD Allen, Y Alaghband, EA Kramár, N Ru, B Petit, V Grilj, MS Petronek, ... Neuro-oncology 25 (5), 927-939, 2023 | 38 | 2023 |
Utilization of redox modulating small molecules that selectively act as pro-oxidants in cancer cells to open a therapeutic window for improving cancer therapy MS Petronek, JM Stolwijk, SD Murray, EJ Steinbach, Y Zakharia, ... Redox biology 42, 101864, 2021 | 30 | 2021 |
Iron–sulfur cluster biogenesis as a critical target in cancer MS Petronek, DR Spitz, BG Allen Antioxidants 10 (9), 1458, 2021 | 29 | 2021 |
Pharmacological ascorbate improves the response to platinum-based chemotherapy in advanced stage non-small cell lung cancer M Furqan, T Abu-Hejleh, LM Stephens, SM Hartwig, SL Mott, CF Pulliam, ... Redox biology 53, 102318, 2022 | 27 | 2022 |
Utilization of pharmacological ascorbate to enhance hydrogen peroxide-mediated radiosensitivity in cancer therapy Z Mehdi, MS Petronek, JM Stolwijk, KA Mapuskar, AL Kalen, GR Buettner, ... International journal of molecular sciences 22 (19), 10880, 2021 | 20 | 2021 |
Neoadjuvant radiotherapy-related wound morbidity in soft tissue sarcoma: perspectives for radioprotective agents CM Callaghan, MM Hasibuzzaman, SN Rodman, JE Goetz, KA Mapuskar, ... Cancers 12 (8), 2258, 2020 | 20 | 2020 |
Magnetic resonance imaging (MRI) of pharmacological ascorbate-induced iron redox state as a biomarker in subjects undergoing radio-chemotherapy CM Cushing, MS Petronek, KL Bodeker, S Vollstedt, HA Brown, E Opat, ... Redox biology 38, 101804, 2021 | 19 | 2021 |
Pharmacological ascorbate as a novel therapeutic strategy to enhance cancer immunotherapy A Zaher, LM Stephens, AM Miller, SM Hartwig, JM Stolwijk, MS Petronek, ... Frontiers in immunology 13, 989000, 2022 | 16 | 2022 |
The effect of concurrent stereotactic body radiation and anti-PD-1 therapy for recurrent metastatic sarcoma CM Callaghan, SN Seyedin, IH Mohiuddin, KL Hawkes, MS Petronek, ... Radiation research 194 (2), 124-132, 2020 | 16 | 2020 |
Magnetite nanoparticles as a kinetically favorable source of iron to enhance GBM response to chemoradiosensitization with pharmacological ascorbate MS Petronek, N Teferi, JM Caster, JM Stolwijk, A Zaher, JM Buatti, ... Redox biology 62, 102651, 2023 | 14 | 2023 |
Magnetic Resonance Imaging of Iron Metabolism with T2* Mapping Predicts an Enhanced Clinical Response to Pharmacologic Ascorbate in Patients with GBM MS Petronek, V Monga, KL Bodeker, M Kwofie, CY Lee, KA Mapuskar, ... Clinical Cancer Research 30 (2), 283-293, 2024 | 13 | 2024 |
Avasopasem manganese (GC4419) protects against cisplatin-induced chronic kidney disease: An exploratory analysis of renal metrics from a randomized phase 2b clinical trial in … KA Mapuskar, GV Martinez, CF Pulliam, MS Petronek, EJ Steinbach, ... Redox biology 60, 102599, 2023 | 12 | 2023 |
Maintenance of genome integrity by the late-acting cytoplasmic iron-sulfur assembly (CIA) complex MS Petronek, BG Allen Frontiers in genetics 14, 1152398, 2023 | 12 | 2023 |
Oxidation of ferumoxytol by ionizing radiation releases iron. An electron paramagnetic resonance study MS Petronek, DR Spitz, GR Buettner, BG Allen Journal of radiation research 63 (3), 378-384, 2022 | 9 | 2022 |
Quantum chemical insight into the effects of the local electron environment on T2*-based MRI MS Petronek, JJ St-Aubin, CY Lee, DR Spitz, EG Gillan, BG Allen, ... Scientific reports 11 (1), 20817, 2021 | 9 | 2021 |
Polyoxometalate nanoparticles as a potential glioblastoma therapeutic via lipid-mediated cell death MS Petronek, BG Allen, G Luthe, JM Stolwijk International journal of molecular sciences 23 (15), 8263, 2022 | 8 | 2022 |
Depletion of Labile Iron Induces Replication Stress and Enhances Responses to Chemoradiation in Non-Small-Cell Lung Cancer K Bayanbold, M Singhania, MA Fath, CC Searby, JM Stolwijk, JB Henrich, ... Antioxidants 12 (11), 2005, 2023 | 7 | 2023 |