Heng Pan
Heng Pan
Peking University Third Hospital
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The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development
A Ortega-Molina, IW Boss, A Canela, H Pan, Y Jiang, C Zhao, M Jiang, ...
Nature medicine 21 (10), 1199-1208, 2015
TET proteins safeguard bivalent promoters from de novo methylation in human embryonic stem cells
N Verma, H Pan, LC Doré, A Shukla, QV Li, B Pelham-Webb, V Teijeiro, ...
Nature genetics 50 (1), 83-95, 2018
Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer
L Puca, K Gavyert, V Sailer, V Conteduca, E Dardenne, M Sigouros, ...
Science translational medicine 11 (484), eaav0891, 2019
Epigenomic evolution in diffuse large B-cell lymphomas
H Pan, Y Jiang, M Boi, F Tabbň, D Redmond, K Nie, M Ladetto, ...
Nature communications 6 (1), 1-12, 2015
QSER1 protects DNA methylation valleys from de novo methylation
G Dixon, H Pan, D Yang, BP Rosen, T Jashari, N Verma, J Pulecio, ...
Science 372 (6538), eabd0875, 2021
Discovery of candidate DNA methylation cancer driver genes
H Pan, L Renaud, R Chaligne, J Bloehdorn, E Tausch, D Mertens, ...
Cancer discovery 11 (9), 2266-2281, 2021
Epigenetic reprogramming sensitizes immunologically silent EBV+ lymphomas to virus-directed immunotherapy
T Dalton, E Doubrovina, D Pankov, R Reynolds, H Scholze, A Selvakumar, ...
Blood, The Journal of the American Society of Hematology 135 (21), 1870-1881, 2020
Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes
D Liu, JE Shoag, D Poliak, RS Goueli, V Ravikumar, D Redmond, ...
Nature communications 11 (1), 1987, 2020
Extracellular matrix in synthetic hydrogel‐based prostate cancer organoids regulate therapeutic response to EZH2 and DRD2 inhibitors
MJ Mosquera, S Kim, R Bareja, Z Fang, S Cai, H Pan, M Asad, ML Martin, ...
Advanced Materials 34 (2), 2100096, 2022
CIC is a critical regulator of neuronal differentiation
I Hwang, H Pan, J Yao, O Elemento, H Zheng, J Paik
JCI insight 5 (9), 2020
Therapeutic efficacy of the bromodomain inhibitor OTX015/MK-8628 in ALK-positive anaplastic large cell lymphoma: an alternative modality to overcome resistant phenotypes
M Boi, M Todaro, V Vurchio, SN Yang, J Moon, I Kwee, A Rinaldi, H Pan, ...
Oncotarget 7 (48), 79637, 2016
TETs regulate proepicardial cell migration through extracellular matrix organization during zebrafish cardiogenesis
Y Lan, H Pan, C Li, KM Banks, J Sam, B Ding, O Elemento, MG Goll, ...
Cell reports 26 (3), 720-732. e4, 2019
Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia
J Bloehdorn, A Braun, A Taylor-Weiner, BMC Jebaraj, S Robrecht, ...
Nature Communications 12 (1), 5395, 2021
Tumor-induced double positive T cells display distinct lineage commitment mechanisms and functions
SE Schad, A Chow, L Mangarin, H Pan, J Zhang, N Ceglia, JX Caushi, ...
Journal of Experimental Medicine 219 (6), e20212169, 2022
Stage-specific regulation of DNA methylation by TET enzymes during human cardiac differentiation
Y Lan, KM Banks, H Pan, N Verma, GR Dixon, T Zhou, B Ding, ...
Cell Reports 37 (10), 2021
Epigenetic analysis identifies factors driving racial disparity in prostate cancer
R Rai, SS Yadav, H Pan, I Khan, J O'Connor, M Alshalalfa, E Davicioni, ...
Cancer Reports 2 (2), e1153, 2019
A FOXO1-dependent transcription network is a targetable vulnerability of mantle cell lymphomas
JY Jang, I Hwang, H Pan, J Yao, L Alinari, E Imada, C Zanettini, MJ Kluk, ...
The Journal of Clinical Investigation 132 (24), 2022
Analyzing DNA methylation patterns during tumor evolution
H Pan, O Elemento
Cancer Systems Biology: Methods and Protocols, 27-53, 2018
Abstract LB-064: characterization of the tumor suppressor function of the lysine-specific methyltransferase KMT2D in follicular lymphoma
A Ortega-Molina, I Boss, H Pan, Y Jiang, D Hu, X Gao, R Shaknovich, ...
Cancer Research 75 (15_Supplement), LB-064-LB-064, 2015
Epigenomic evolution in diffuse large B-cell lymphomas
H Pan, Y Jiang, D Redmond, K Nie, L Cerchietti, R Shaknovich, ...
Blood 122 (21), 634, 2013
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