M. Celeste Simon
M. Celeste Simon
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Hypoxia-inducible factors and the response to hypoxic stress
AJ Majmundar, WJ Wong, MC Simon
Molecular cell 40 (2), 294-309, 2010
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
NS Chandel, E Maltepe, E Goldwasser, CE Mathieu, MC Simon, ...
Proceedings of the National Academy of Sciences 95 (20), 11715-11720, 1998
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase
MA Selak, SM Armour, ED MacKenzie, H Boulahbel, DG Watson, ...
Cancer cell 7 (1), 77-85, 2005
Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
JE Durbin, R Hackenmiller, MC Simon, DE Levy
Cell 84 (3), 443-450, 1996
HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression
B Keith, RS Johnson, MC Simon
Nature Reviews Cancer 12 (1), 9-22, 2012
Requirement of transcription factor PU. 1 in the development of multiple hematopoietic lineages
EW Scott, MC Simon, J Anastasi, H Singh
Science 265 (5178), 1573-1577, 1994
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues
T Lindsten, AJ Ross, A King, WX Zong, JC Rathmell, HA Shiels, E Ulrich, ...
Molecular cell 6 (6), 1389-1399, 2000
Mop3 is an essential component of the master circadian pacemaker in mammals
MK Bunger, LD Wilsbacher, SM Moran, C Clendenin, LA Radcliffe, ...
Cell 103 (7), 1009-1017, 2000
Differential roles of hypoxia-inducible factor 1α (HIF-1α) and HIF-2α in hypoxic gene regulation
CJ Hu, LY Wang, LA Chodosh, B Keith, MC Simon
Molecular and cellular biology 23 (24), 9361-9374, 2003
Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing
RD Guzy, B Hoyos, E Robin, H Chen, L Liu, KD Mansfield, MC Simon, ...
Cell metabolism 1 (6), 401-408, 2005
The impact of O2 availability on human cancer
JA Bertout, SA Patel, MC Simon
Nature Reviews Cancer 8 (12), 967-975, 2008
Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1
L Pevny, MC Simon, E Robertson, WH Klein, SF Tsai, V D'Agati, SH Orkin, ...
Nature 349 (6306), 257-260, 1991
The tumor microenvironment
NM Anderson, MC Simon
Current Biology 30 (16), R921-R925, 2020
Hypoxia-inducible factors, stem cells, and cancer
B Keith, MC Simon
Cell 129 (3), 465-472, 2007
Hypoxia-induced angiogenesis: good and evil
BL Krock, N Skuli, MC Simon
Genes & cancer 2 (12), 1117-1133, 2011
Stabilization of wild-type p53 by hypoxia-inducible factor 1α
WG An, M Kanekal, MC Simon, E Maltepe, MV Blagosklonny, LM Neckers
Nature 392 (6674), 405-408, 1998
The role of oxygen availability in embryonic development and stem cell function
MC Simon, B Keith
Nature reviews Molecular cell biology 9 (4), 285-296, 2008
Characterization of a murine Ahr null allele: involvement of the Ah receptor in hepatic growth and development.
JV Schmidt, GH Su, JK Reddy, MC Simon, CA Bradfield
Proceedings of the National Academy of Sciences 93 (13), 6731-6736, 1996
HIF-2α regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth
KL Covello, J Kehler, H Yu, JD Gordan, AM Arsham, CJ Hu, PA Labosky, ...
Genes & development 20 (5), 557-570, 2006
Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability
DR Wise, PS Ward, JES Shay, JR Cross, JJ Gruber, UM Sachdeva, ...
Proceedings of the National Academy of Sciences 108 (49), 19611-19616, 2011
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