Hugues Abriel

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Jean-Sebastien RougierSenior Teaching and Research assistant, Universitiy of Bern, SwitzerlandVerified email at ibmm.unibe.ch
Olivier StaubUniversity of LausanneVerified email at unil.ch
Mohamed Yassine AmarouchProfessor of Physiology, Multidisciplinary Faculty of Taza, University Sidi Mohamed Ben Abdallah ofVerified email at usmba.ac.ma
Ludovic GilletClinical Scientist - Roche Diagnostics InternationalVerified email at roche.com
Thomas JespersenProfessor, University of CopenhagenVerified email at sund.ku.dk
Thierry PedrazziniUniversity of Lausanne Medical SchoolVerified email at chuv.ch
Alain CoulombeICAN - Institute of CardioMetabolism and Nutrition Sorbonne Université, Paris, France Faculté deVerified email at upmc.fr
Michihiro TATEYAMAVerified email at nips.ac.jp
vincent probstuniversité de nantesVerified email at chu-nantes.fr
Xander Wehrens, MD PhDDirector, Cardiovascular Research Institute, Baylor College of MedicineVerified email at bcm.edu
Daniela RotinHospital for Sick children, Cell Biology Program, and Biochemistry Department, University of TorontoVerified email at sickkids.ca
Silvia G Priori, MD ,PhDICS Maugeri, IRCCS; Dept Molecular Medicine, Univ of Pavia, Italy -Verified email at fsm.it
Carlo NapolitanoUniversity of Pavia and Molecular Cardiology ICS Maugeri, Pavia, ItalyVerified email at fsm.it
Candido CaboNew York City College of Technology/CUNY and Courant Institute/New York UniversityVerified email at citytech.cuny.edu
Ozhathil Lijo CherianSophion Bioscience, DenmarkVerified email at sophion.com
Andrea DomenighettiShirley Ryan AbilityLabVerified email at sralab.org
Carol Ann Remme MD PhDDepartment of Experimental Cardiology, Academic Medical Center, AmsterdamVerified email at amc.uva.nl
Søren-Peter OlesenProfessor, University of CopenhagenVerified email at sund.ku.dk
Johannes LoffingUniversity of ZurichVerified email at anatom.uzh.ch
Pascale GuicheneySorbonne UniversityVerified email at sorbonne-universite.fr

Hugues Abriel

Inst. of Biochemistry and Molecular Medicine, University of Bern, Switzerland

Verified email at ibmm.unibe.ch - Homepage

ion channels channelopathies cardiac electrophysiology cellular electrophysiology


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Defective regulation of the epithelial Na⁺ channel by Nedd4 in Liddle's syndrome H Abriel, J Loffing, JF Rebhun, JH Pratt, L Schild, JD Horisberger, D Rotin, ... The Journal of clinical investigation 103 (5), 667-673, 1999	453	1999
Stereoselective Block of hERG Channel by (S)‐Methadone and QT Interval Prolongation in CYP2B6 Slow Metabolizers CB Eap, S Crettol, JS Rougier, J Schläpfer, L Sintra Grilo, JJ Déglon, ... Clinical Pharmacology & Therapeutics 81 (5), 719-728, 2007	333	2007
Cardiac sodium channel Nav1. 5 and interacting proteins: physiology and pathophysiology H Abriel Journal of molecular and cellular cardiology 48 (1), 2-11, 2010	312	2010
Cardiac Sodium Channel Na_v1.5 Is Regulated by a Multiprotein Complex Composed of Syntrophins and Dystrophin B Gavillet, JS Rougier, AA Domenighetti, R Behar, C Boixel, P Ruchat, ... Circulation research 99 (4), 407-414, 2006	283	2006
Regulation of the epithelial Na+ channel by Nedd4 and ubiquitination O Staub, H Abriel, P Plant, T Ishikawa, V Kanelis, R Saleki, ... Kidney international 57 (3), 809-815, 2000	278	2000
SAP97 and Dystrophin Macromolecular Complexes Determine Two Pools of Cardiac Sodium Channels Na_v1.5 in Cardiomyocytes S Petitprez, AF Zmoos, J Ogrodnik, E Balse, N Raad, S El-Haou, M Albesa, ... Circulation research 108 (3), 294-304, 2011	276	2011
Characterization of sodium channel α-and β-subunits in rat and mouse cardiac myocytes JD Malhotra, C Chen, I Rivolta, H Abriel, R Malhotra, LN Mattei, ... Circulation 103 (9), 1303-1310, 2001	273	2001
Cardiac Voltage-Gated Sodium Channel Na_v1.5 Is Regulated by Nedd4-2 Mediated Ubiquitination MX van Bemmelen, JS Rougier, B Gavillet, F Apothéloz, D Daidié, ... Circulation research 95 (3), 284-291, 2004	253	2004
Identification of a novel loss-of-function calcium channel gene mutation in short QT syndrome (SQTS6) C Templin, JR Ghadri, JS Rougier, A Baumer, V Kaplan, M Albesa, ... European heart journal 32 (9), 1077-1088, 2011	249	2011
Brugada syndrome and fever: Genetic and molecular characterization of patients carrying SCN5A mutations DI Keller, JS Rougier, JP Kucera, N Benammar, V Fressart, P Guicheney, ... Cardiovascular research 67 (3), 510-519, 2005	242	2005
Inherited Brugada and long QT-3 syndrome mutations of a single residue of the cardiac sodium channel confer distinct channel and clinical phenotypes I Rivolta, H Abriel, M Tateyama, H Liu, M Memmi, P Vardas, C Napolitano, ... Journal of Biological Chemistry 276 (33), 30623-30630, 2001	232	2001
Refining the molecular organization of the cardiac intercalated disc SH Vermij, H Abriel, TAB van Veen Cardiovascular research 113 (3), 259-275, 2017	209	2017
Regulation of the voltage-gated cardiac sodium channel Nav1. 5 by interacting proteins H Abriel, RS Kass Trends in cardiovascular medicine 15 (1), 35-40, 2005	203	2005
Cardiac sodium channel NaV1. 5 distribution in myocytes via interacting proteins: the multiple pool model D Shy, L Gillet, H Abriel Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1833 (4), 886-894, 2013	195	2013
Nedd4. 1-mediated ubiquitination and subsequent recruitment of Tsg101 ensure HTLV-1 Gag trafficking towards the multivesicular body pathway prior to virus budding V Blot, F Perugi, B Gay, MC Prévost, L Briant, F Tangy, H Abriel, O Staub, ... Journal of cell science 117 (11), 2357-2367, 2004	178	2004
Molecular genetics and functional anomalies in a series of 248 Brugada cases with 11 mutations in the TRPM4 channel H Liu, S Chatel, C Simard, N Syam, L Salle, V Probst, J Morel, G Millat, ... PloS one 8 (1), e54131, 2013	168	2013
Molecular determinants of voltage-gated sodium channel regulation by the Nedd4/Nedd4-like proteins JS Rougier, MX van Bemmelen, MC Bruce, T Jespersen, B Gavillet, ... American Journal of Physiology-Cell Physiology 288 (3), C692-C701, 2005	162	2005
Cardiac channelopathies: genetic and molecular mechanisms H Abriel, EV Zaklyazminskaya Gene 517 (1), 1-11, 2013	161	2013
The KCNQ1 potassium channel is down-regulated by ubiquitylating enzymes of the Nedd4/Nedd4-like family T Jespersen, M Membrez, CS Nicolas, B Pitard, O Staub, SP Olesen, ... Cardiovascular research 74 (1), 64-74, 2007	161	2007
Novel Arrhythmogenic Mechanism Revealed by a Long-QT Syndrome Mutation in the Cardiac Na⁺ Channel H Abriel, C Cabo, XHT Wehrens, I Rivolta, HK Motoike, M Memmi, ... Circulation research 88 (7), 740-745, 2001	154	2001

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