Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells DA Zacharias, JD Violin, AC Newton, RY Tsien Science 296 (5569), 913-916, 2002 | 2703 | 2002 |
Protein kinase C: structure, function, and regulation AC Newton Journal of biological chemistry 270 (48), 28495-28498, 1995 | 2391 | 1995 |
Regulation of protein kinase C AC Newton Current opinion in cell biology 9 (2), 161-167, 1997 | 1280 | 1997 |
Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions AC Newton Chemical reviews 101 (8), 2353-2364, 2001 | 1257 | 2001 |
PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth T Gao, F Furnari, AC Newton Molecular cell 18 (1), 13-24, 2005 | 1149 | 2005 |
Protein kinase C isozymes and the regulation of diverse cell responses EC Dempsey, AC Newton, D Mochly-Rosen, AP Fields, ME Reyland, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 279 (3 …, 2000 | 1064 | 2000 |
Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm AC Newton Biochemical Journal 370 (2), 361-371, 2003 | 1054 | 2003 |
Regulation of protein kinase C ζ by PI 3-kinase and PDK-1 MM Chou, W Hou, J Johnson, LK Graham, MH Lee, CS Chen, AC Newton, ... Current Biology 8 (19), 1069-1078, 1998 | 805 | 1998 |
Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site A Toker, AC Newton Journal of Biological Chemistry 275 (12), 8271-8274, 2000 | 752 | 2000 |
PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms J Brognard, E Sierecki, T Gao, AC Newton Molecular cell 25 (6), 917-931, 2007 | 724 | 2007 |
A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C JD Violin, J Zhang, RY Tsien, AC Newton The Journal of cell biology 161 (5), 899-909, 2003 | 660 | 2003 |
The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C V Facchinetti, W Ouyang, H Wei, N Soto, A Lazorchak, C Gould, C Lowry, ... The EMBO journal 27 (14), 1932-1943, 2008 | 656 | 2008 |
Protein kinase C is regulated in vivo by three functionally distinct phosphorylations LM Keranen, EM Dutil, AC Newton Current Biology 5 (12), 1394-1403, 1995 | 634 | 1995 |
Protein kinase C: poised to signal AC Newton American Journal of Physiology-Endocrinology And Metabolism 298 (3), E395-E402, 2010 | 626 | 2010 |
Cellular signaling: pivoting around PDK-1 A Toker, AC Newton Cell 103 (2), 185-188, 2000 | 558 | 2000 |
Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1) EM Dutil, A Toker, AC Newton Current Biology 8 (25), 1366-1375, 1998 | 542 | 1998 |
Taxonomy and function of C1 protein kinase C homology domains JH Hurley, AC Newton, PJ Parker, PM Blumberg, Y Nishizuka Protein Science 6 (2), 477-480, 1997 | 474 | 1997 |
Cancer-associated protein kinase C mutations reveal kinase’s role as tumor suppressor CE Antal, AM Hudson, E Kang, C Zanca, C Wirth, NL Stephenson, ... Cell 160 (3), 489-502, 2015 | 362 | 2015 |
Protein kinase C: a paradigm for regulation of protein function by two membrane-targeting modules AC Newton, JE Johnson Biochimica et Biophysica Acta (BBA)-Reviews on Biomembranes 1376 (2), 155-172, 1998 | 358 | 1998 |
p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1) CC King, EMM Gardiner, FT Zenke, BP Bohl, AC Newton, BA Hemmings, ... Journal of Biological Chemistry 275 (52), 41201-41209, 2000 | 298 | 2000 |