Alexandra Newton
Alexandra Newton
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Partitioning of lipid-modified monomeric GFPs into membrane microdomains of live cells
DA Zacharias, JD Violin, AC Newton, RY Tsien
Science 296 (5569), 913-916, 2002
Protein kinase C: structure, function, and regulation
AC Newton
Journal of biological chemistry 270 (48), 28495-28498, 1995
Regulation of protein kinase C
AC Newton
Current opinion in cell biology 9 (2), 161-167, 1997
Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions
AC Newton
Chemical reviews 101 (8), 2353-2364, 2001
PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth
T Gao, F Furnari, AC Newton
Molecular cell 18 (1), 13-24, 2005
Protein kinase C isozymes and the regulation of diverse cell responses
EC Dempsey, AC Newton, D Mochly-Rosen, AP Fields, ME Reyland, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 279 (3 …, 2000
Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm
AC Newton
Biochemical Journal 370 (2), 361-371, 2003
Regulation of protein kinase C ζ by PI 3-kinase and PDK-1
MM Chou, W Hou, J Johnson, LK Graham, MH Lee, CS Chen, AC Newton, ...
Current Biology 8 (19), 1069-1078, 1998
Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site
A Toker, AC Newton
Journal of Biological Chemistry 275 (12), 8271-8274, 2000
PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms
J Brognard, E Sierecki, T Gao, AC Newton
Molecular cell 25 (6), 917-931, 2007
The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C
V Facchinetti, W Ouyang, H Wei, N Soto, A Lazorchak, C Gould, C Lowry, ...
The EMBO journal 27 (14), 1932-1943, 2008
A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C
JD Violin, J Zhang, RY Tsien, AC Newton
The Journal of cell biology 161 (5), 899-909, 2003
Protein kinase C is regulated in vivo by three functionally distinct phosphorylations
LM Keranen, EM Dutil, AC Newton
Current Biology 5 (12), 1394-1403, 1995
Protein kinase C: poised to signal
AC Newton
American Journal of Physiology-Endocrinology And Metabolism 298 (3), E395-E402, 2010
Cellular signaling: pivoting around PDK-1
A Toker, AC Newton
Cell 103 (2), 185-188, 2000
Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1)
EM Dutil, A Toker, AC Newton
Current Biology 8 (25), 1366-1375, 1998
Taxonomy and function of C1 protein kinase C homology domains
JH Hurley, AC Newton, PJ Parker, PM Blumberg, Y Nishizuka
Protein Science 6 (2), 477-480, 1997
Protein kinase C: a paradigm for regulation of protein function by two membrane-targeting modules
AC Newton, JE Johnson
Biochimica et Biophysica Acta (BBA)-Reviews on Biomembranes 1376 (2), 155-172, 1998
Cancer-associated protein kinase C mutations reveal kinase’s role as tumor suppressor
CE Antal, AM Hudson, E Kang, C Zanca, C Wirth, NL Stephenson, ...
Cell 160 (3), 489-502, 2015
p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1)
CC King, EMM Gardiner, FT Zenke, BP Bohl, AC Newton, BA Hemmings, ...
Journal of Biological Chemistry 275 (52), 41201-41209, 2000
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