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Stephen Gately
Stephen Gately
CEO Translational Drug Development
Verified email at td2inc.com
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Cited by
Cited by
Year
Combined effects of angiostatin and ionizing radiation in antitumour therapy
HJ Mauceri, NN Hanna, MA Beckett, DH Gorski, MJ Staba, KA Stellato, ...
Nature 394 (6690), 287-291, 1998
8651998
The contributions of cyclooxygenase-2 to tumor angiogenesis
S Gately
Cancer and metastasis reviews 19, 19-27, 2000
5622000
Multiple roles of COX-2 in tumor angiogenesis: a target for antiangiogenic therapy
S Gately, WW Li
Seminars in Oncology 31, 2-11, 2004
5142004
The mechanism of cancer-mediated conversion of plasminogen to the angiogenesis inhibitor angiostatin
S Gately, P Twardowski, MS Stack, DL Cundiff, D Grella, FJ Castellino, ...
Proceedings of the National Academy of Sciences 94 (20), 10868-10872, 1997
4051997
Inhibition of angiogenesis and tumor growth in the brain. Suppression of endothelial cell turnover by penicillamine and the depletion of copper, an angiogenic cofactor.
SS Brem, D Zagzag, AM Tsanaclis, S Gately, MP Elkouby, SE Brien
The American journal of pathology 137 (5), 1121, 1990
2961990
Human prostate carcinoma cells express enzymatic activity that converts human plasminogen to the angiogenesis inhibitor, angiostatin
S Gately, P Twardowski, MS Stack, M Patrick, L Boggio, DL Cundiff, ...
Cancer Research 56 (21), 4887-4890, 1996
2891996
Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin
DH Gorski, HJ Mauceri, RM Salloum, S Gately, S Hellman, MA Beckett, ...
Cancer research 58 (24), 5686-5689, 1998
2711998
Expression of plasminogen activator inhibitor type 1 by human prostate carcinoma cells inhibits primary tumor growth, tumor-associated angiogenesis, and metastasis to lung and …
GA Soff, J Sanderowitz, S Gately, E Verrusio, I Weiss, S Brem, HC Kwaan
The Journal of clinical investigation 96 (6), 2593-2600, 1995
2131995
β-carboline compounds, including harmine, inhibit DYRK1A and tau phosphorylation at multiple Alzheimer's disease-related sites
D Frost, B Meechoovet, T Wang, S Gately, M Giorgetti, I Shcherbakova, ...
PloS one 6 (5), e19264, 2011
2022011
Suramin, an anticancer and angiosuppressive agent, inhibits endothelial cell binding of basic fibroblast growth factor, migration, proliferation, and induction of urokinase …
S Takano, S Gately, ME Neville, WF Herblin, JL Gross, H Engelhard, ...
Cancer research 54 (10), 2654-2660, 1994
1891994
Angiostatin inhibits endothelial and melanoma cellular invasion by blocking matrix-enhanced plasminogen activation
MS Stack, S Gately, LM Bafetti, JJ Enghild, GA Soff
Biochemical journal 340 (1), 77-84, 1999
1821999
Antiangiogenic scheduling of lower dose cancer chemotherapy.
S Gately, R Kerbel
Cancer journal (Sudbury, Mass.) 7 (5), 427-436, 2001
1772001
Novel therapeutics with enhanced biological activity generated by the strategic introduction of silicon isosteres into known drug scaffolds
S Gately, R West
Drug Development Research 68 (4), 156-163, 2007
1672007
Therapeutic potential of selective cyclooxygenase-2 inhibitors in the management of tumor angiogenesis
S Gately, R Kerbel
Progress in experimental tumor research 37, 179-192, 2003
1652003
Human Angiostatin Inhibits Murine Hemangioendothelioma Tumor Growth in Vivo
BJ Lannutti, ST Gately, ME Quevedo, GA Soff, AS Paller
Cancer research 57 (23), 5277-5280, 1997
1451997
Diverse roles of macrophage matrix metalloproteinases in tissue destruction and tumor growth
SD Shapiro
Thrombosis and haemostasis 82 (08), 846-849, 1999
1351999
Immunolocalization of basic fibroblast growth factor to the micro vasculature of human brain tumors
S Brem, AMC Tsanaclis, S Gately, JL Gross, WF Herblin
Cancer 70 (11), 2673-2680, 1992
1351992
Development of potent autophagy inhibitors that sensitize oncogenic BRAF V600E mutant melanoma tumor cells to vemurafenib
ML Goodall, T Wang, KR Martin, MG Kortus, AL Kauffman, JM Trent, ...
Autophagy 10 (6), 1120-1136, 2014
1272014
Smooth muscle cell expression of type I cyclic GMP-dependent protein kinase is suppressed by continuous exposure to nitrovasodilators, theophylline, cyclic GMP, and cyclic AMP.
GA Soff, TL Cornwell, DL Cundiff, S Gately, TM Lincoln
The Journal of clinical investigation 100 (10), 2580-2587, 1997
1251997
Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia
JP McKearn, G Gordon, JJ Cunningham, ST Gately, AT Koki, JL Masferrer
US Patent 6,858,598, 2005
802005
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