Seguir
Patrick Nygren
Patrick Nygren
Senior Manager, Oncology Resource Group
Dirección de correo verificada de uw.edu
Título
Citado por
Citado por
Año
Local protein kinase A action proceeds through intact holoenzymes
FD Smith, JL Esseltine, PJ Nygren, D Veesler, DP Byrne, M Vonderach, ...
Science 356 (6344), 1288-1293, 2017
1952017
AKAP150 Contributes to Enhanced Vascular Tone by Facilitating Large-Conductance Ca2+-Activated K+ Channel Remodeling in Hyperglycemia and Diabetes …
MA Nystoriak, M Nieves-Cintrón, PJ Nygren, SA Hinke, CB Nichols, ...
Circulation Research 114 (4), 607-615, 2014
1162014
Architecture and dynamics of an A-kinase anchoring protein 79 (AKAP79) signaling complex
MG Gold, F Stengel, PJ Nygren, CR Weisbrod, JE Bruce, CV Robinson, ...
Proceedings of the National Academy of Sciences 108 (16), 6426-6431, 2011
982011
Anchored phosphatases modulate glucose homeostasis
SA Hinke, MF Navedo, A Ulman, JL Whiting, PJ Nygren, G Tian, ...
The EMBO journal 31 (20), 3991-4004, 2012
792012
Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-kinase anchoring proteins
FD Smith, MH Omar, PJ Nygren, J Soughayer, N Hoshi, HT Lau, ...
Proceedings of the National Academy of Sciences 115 (49), E11465-E11474, 2018
372018
Protein kinase A opposes the phosphorylation-dependent recruitment of glycogen synthase kinase 3β to A-kinase anchoring protein 220
JL Whiting, PJ Nygren, BJ Tunquist, LK Langeberg, OM Seternes, ...
Journal of Biological Chemistry 290 (32), 19445-19457, 2015
312015
Therapeutic strategies for anchored kinases and phosphatases: exploiting short linear motifs and intrinsic disorder
PJ Nygren, JD Scott
Frontiers in pharmacology 6, 156203, 2015
312015
AKAP150 participates in calcineurin/NFAT activation during the down-regulation of voltage-gated K+ currents in ventricular myocytes following myocardial infarction
M Nieves-Cintrón, D Hirenallur-Shanthappa, PJ Nygren, SA Hinke, ...
Cellular signalling 28 (7), 733-740, 2016
282016
Regulation of the phosphatase PP2B by protein–protein interactions
PJ Nygren, JD Scott
Biochemical Society Transactions 44 (5), 1313-1319, 2016
272016
Intrinsic disorder within AKAP79 fine-tunes anchored phosphatase activity toward substrates and drug sensitivity
PJ Nygren, S Mehta, DK Schweppe, LK Langeberg, JL Whiting, ...
Elife 6, e30872, 2017
262017
A-kinase anchoring protein 79/150 recruits protein kinase C to phosphorylate roundabout receptors
BK Samelson, BB Gore, JL Whiting, PJ Nygren, AM Purkey, M Colledge, ...
Journal of Biological Chemistry 290 (22), 14107-14119, 2015
152015
AKAP150 Contributes to Enhanced Vascular Tone by Facilitating BKCa Channel Remodeling in Hyperglycemia and Diabetes
MA Nystoriak, M Nieves-Cintrón, PJ Nygren, SA Hinke, CB Nichols, ...
Circulation research 114 (4), 607, 2014
12014
Structural basis for phosphatase regulation by the anchoring protein AKAP79
PJ Nygren
2015
Calcineurin Localization By AKAP150 in Insulin Secretion
SA Hinke, PJ Nygren, JD Scott
ENDOCRINE REVIEWS 35 (3), 2014
2014
Molecular basis for a bipartite phosphatase interaction with the anchoring protein AKAP79
PJ Nygren, MG Gold, CR Weisbrod, JE Bruce, JD Scott
The FASEB Journal 27, 1043.1-1043.1, 2013
2013
Channel Remodeling Ca
CY Chen, JL Puglisi, L Izu, DM Bers, ML Dell'Acqua, J Scott, ...
2013
Inventory of supplementary information: Supplementary figures (6) Supplementary figure legends Supplementary materials and methods Supplementary references
SA Hinke, MF Navedo, A Ulman, JL Whiting, PJ Nygren, G Tian, ...
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–17