| Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm KF Liem Jr, G Tremml, H Roelink, TM Jessell Cell 82 (6), 969-979, 1995 | 1320 | 1995 |
| Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis H Roelink, JA Porter, C Chiang, Y Tanabe, DT Chang, PA Beachy, ... Cell 81 (3), 445-455, 1995 | 1143 | 1995 |
| Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity J Ericson, S Morton, A Kawakami, H Roelink, TM Jessell Cell 87 (4), 661-673, 1996 | 1098 | 1996 |
| Floor plate and motor neuron induction by vhh-1, a vertebrate homolog of hedgehog expressed by the notochord H Roelink, A Augsburger, J Heemskerk, V Korzh, S Norlin, AR i Altaba, ... Cell 76 (4), 761-775, 1994 | 1083 | 1994 |
| The teratogenic Veratrum alkaloid cyclopamine inhibits Sonic hedgehog signal transduction JP Incardona, W Gaffield, RP Kapur, H Roelink Development 125 (18), 3553-3562, 1998 | 835 | 1998 |
| Determination of neuroepithelial cell fate: induction of the oligodendrocyte lineage by ventral midline cells and sonic hedgehog NP Pringle, WP Yu, S Guthrie, H Roelink, A Lumsden, AC Peterson, ... Developmental biology 177 (1), 30-42, 1996 | 381 | 1996 |
| WNT signaling in the control of hair growth and structure SE Millar, K Willert, PC Salinas, H Roelink, R Nusse, DJ Sussman, ... Developmental biology 207 (1), 133-149, 1999 | 353 | 1999 |
| Expression of two members of the Wnt family during mouse development--restricted temporal and spatial patterns in the developing neural tube. H Roelink, R Nusse Genes & development 5 (3), 381-388, 1991 | 336 | 1991 |
| Sonic hedgehog promotes rod photoreceptor differentiation in mammalian retinal cells in vitro EM Levine, H Roelink, J Turner, TA Reh Journal of Neuroscience 17 (16), 6277-6288, 1997 | 271 | 1997 |
| Wnt-3, a gene activated by proviral insertion in mouse mammary tumors, is homologous to int-1/Wnt-1 and is normally expressed in mouse embryos and adult brain. H Roelink, E Wagenaar, S Lopes da Silva, R Nusse Proceedings of the National Academy of Sciences 87 (12), 4519-4523, 1990 | 254 | 1990 |
| Receptor-mediated endocytosis of soluble and membrane-tethered Sonic hedgehog by Patched-1 JP Incardona, JH Lee, CP Robertson, K Enga, RP Kapur, H Roelink Proceedings of the National Academy of Sciences 97 (22), 12044-12049, 2000 | 248 | 2000 |
| Sonic hedgehog induces the segregation of patched and smoothened in endosomes JP Incardona, J Gruenberg, H Roelink Current Biology 12 (12), 983-995, 2002 | 234 | 2002 |
| Induction of motor neurons by Sonic hedgehog is independent of floor plate differentiation Y Tanabe, H Roelink, TM Jessell Current Biology 5 (6), 651-658, 1995 | 232 | 1995 |
| Wnt signaling is required at distinct stages of development for the induction of the posterior forebrain MM Braun, A Etheridge, A Bernard, CP Robertson, H Roelink Oxford University Press for The Company of Biologists Limited 130 (23), 5579 …, 2003 | 209 | 2003 |
| Cyclopamine inhibition of Sonic hedgehog signal transduction is not mediated through effects on cholesterol transport JP Incardona, W Gaffield, Y Lange, A Cooney, PG Pentchev, S Liu, ... Developmental biology 224 (2), 440-452, 2000 | 153 | 2000 |
| The notch response inhibitor DAPT enhances neuronal differentiation in embryonic stem cell‐derived embryoid bodies independently of sonic hedgehog signaling TQ Crawford, H Roelink Developmental dynamics: an official publication of the American Association …, 2007 | 150 | 2007 |
| Restrictions to floor plate induction by hedgehog and winged-helix genes in the neural tube of frog embryos AR i Altaba, TM Jessell, H Roelink Molecular and Cellular Neuroscience 6 (2), 106-121, 1995 | 136 | 1995 |
| Protein kinase A deficiency causes axially localized neural tube defects in mice Y Huang, H Roelink, GS McKnight Journal of Biological Chemistry 277 (22), 19889-19896, 2002 | 124 | 2002 |
| Sonic hedgehog induces transcription-independent cytoskeletal rearrangement and migration regulated by arachidonate metabolites MF Bijlsma, KS Borensztajn, H Roelink, MP Peppelenbosch, CA Spek Cellular signalling 19 (12), 2596-2604, 2007 | 122 | 2007 |
| The amino-terminal region of Gli3 antagonizes the Shh response and acts in dorsoventral fate specification in the developing spinal cord H Roelink Developmental biology 257 (2), 343-355, 2003 | 115 | 2003 |
