BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1 N Watanabe, M Gavrieli, JR Sedy, J Yang, F Fallarino, SK Loftin, ... Nature immunology 4 (7), 670-679, 2003 | 1069 | 2003 |
B and T lymphocyte attenuator regulates T cell activation through interaction with herpesvirus entry mediator JR Sedy, M Gavrieli, KG Potter, MA Hurchla, RC Lindsley, K Hildner, ... Nature immunology 6 (1), 90-98, 2005 | 814 | 2005 |
B and T lymphocyte attenuator exhibits structural and expression polymorphisms and is highly Induced in anergic CD4+ T cells MA Hurchla, JR Sedy, M Gavrielli, CG Drake, TL Murphy, KM Murphy The Journal of Immunology 174 (6), 3377-3385, 2005 | 223 | 2005 |
The epoxyketone-based proteasome inhibitors carfilzomib and orally bioavailable oprozomib have anti-resorptive and bone-anabolic activity in addition to anti-myeloma effects MA Hurchla, A Garcia-Gomez, MC Hornick, EM Ocio, A Li, JF Blanco, ... Leukemia 27 (2), 430-440, 2013 | 135 | 2013 |
Cutting edge: B and T lymphocyte attenuator and programmed death receptor-1 inhibitory receptors are required for termination of acute allergic airway inflammation C Deppong, TI Juehne, M Hurchla, LD Friend, DD Shah, CM Rose, ... The Journal of Immunology 176 (7), 3909-3913, 2006 | 127 | 2006 |
The ADP receptor P2RY12 regulates osteoclast function and pathologic bone remodeling X Su, DH Floyd, A Hughes, J Xiang, JG Schneider, O Uluckan, E Heller, ... The Journal of clinical investigation 122 (10), 3579-3592, 2012 | 103 | 2012 |
Unexpected role of B and T lymphocyte attenuator in sustaining cell survival during chronic allostimulation MA Hurchla, JR Sedy, KM Murphy The Journal of Immunology 178 (10), 6073-6082, 2007 | 103 | 2007 |
Hedgehog signaling inhibition blocks growth of resistant tumors through effects on tumor microenvironment E Heller, MA Hurchla, J Xiang, X Su, S Chen, J Schneider, KS Joeng, ... Cancer research 72 (4), 897-907, 2012 | 87 | 2012 |
Antagonizing integrin β3 increases immunosuppression in cancer X Su, AK Esser, SR Amend, J Xiang, Y Xu, MH Ross, GC Fox, ... Cancer research 76 (12), 3484-3495, 2016 | 77 | 2016 |
CXCR4 protein epitope mimetic antagonist POL5551 disrupts metastasis and enhances chemotherapy effect in triple-negative breast cancer J Xiang, MA Hurchla, F Fontana, X Su, SR Amend, AK Esser, GJ Douglas, ... Molecular cancer therapeutics 14 (11), 2473-2485, 2015 | 62 | 2015 |
Ligation of B and T lymphocyte attenuator prevents the genesis of experimental cerebral malaria B Lepenies, K Pfeffer, MA Hurchla, TL Murphy, KM Murphy, J Oetzel, ... The Journal of Immunology 179 (6), 4093-4100, 2007 | 62 | 2007 |
Interferon-γ targets cancer cells and osteoclasts to prevent tumor-associated bone loss and bone metastases Z Xu, MA Hurchla, H Deng, O Uluçkan, F Bu, A Berdy, MC Eagleton, ... Journal of Biological Chemistry 284 (7), 4658-4666, 2009 | 60 | 2009 |
Thrombospondin‐1 regulates bone homeostasis through effects on bone matrix integrity and nitric oxide signaling in osteoclasts SR Amend, O Uluckan, M Hurchla, D Leib, D Veis Novack, M Silva, ... Journal of Bone and Mineral Research 30 (1), 106-115, 2015 | 59 | 2015 |
Dissection of platelet and myeloid cell defects by conditional targeting of the β3-integrin subunit EA Morgan, JG Schneider, TE Baroni, Ö Uluçkan, E Heller, MA Hurchla, ... The FASEB Journal 24 (4), 1117, 2010 | 57 | 2010 |
Noncompetitive Modulation of the Proteasome by Imidazoline Scaffolds Overcomes Bortezomib Resistance and Delays MM Tumor Growth in Vivo TA Lansdell, MA Hurchla, J Xiang, S Hovde, KN Weilbaecher, RW Henry, ... ACS chemical biology 8 (3), 578-587, 2013 | 44 | 2013 |
Very Late Antigen-4 (α4β1 Integrin) Targeted PET Imaging of Multiple Myeloma D Soodgupta, MA Hurchla, M Jiang, A Zheleznyak, KN Weilbaecher, ... PloS one 8 (2), e55841, 2013 | 43 | 2013 |
Whole genome sequence of multiple myeloma-prone C57BL/KaLwRij mouse strain suggests the origin of disease involves multiple cell types SR Amend, WC Wilson, L Chu, L Lu, P Liu, D Serie, X Su, Y Xu, D Wang, ... PloS one 10 (5), e0127828, 2015 | 38 | 2015 |
The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice DA Rauch, MA Hurchla, JC Harding, H Deng, LK Shea, MC Eagleton, ... PloS one 5 (12), e15755, 2010 | 31 | 2010 |
Btla signaling in conventional and regulatory lymphocytes coordinately tempers humoral immunity in the intestinal mucosa C Stienne, R Virgen-Slane, L Elmén, M Veny, S Huang, J Nguyen, ... Cell reports 38 (12), 2022 | 14 | 2022 |
Hedgehog-targeted therapeutics uncouple the vicious cycle of bone metastasis MA Hurchla, KN Weilbaecher Oncoimmunology 1 (8), 1411-1413, 2012 | 3 | 2012 |