SARS-CoV-2 replication in airway epithelia requires motile cilia and microvillar reprogramming CT Wu, PV Lidsky, Y Xiao, R Cheng, IT Lee, T Nakayama, S Jiang, W He, ... Cell 186 (1), 112-130. e20, 2023 | 86 | 2023 |
An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins DJ Shon, SA Malaker, K Pedram, E Yang, V Krishnan, O Dorigo, ... Proceedings of the National Academy of Sciences 117 (35), 21299-21307, 2020 | 78 | 2020 |
Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection SB Biering, SA Sarnik, E Wang, JR Zengel, SR Leist, A Schäfer, ... Nature genetics 54 (8), 1078-1089, 2022 | 65 | 2022 |
Revealing the human mucinome SA Malaker, NM Riley, DJ Shon, K Pedram, V Krishnan, O Dorigo, ... Nature Communications 13 (1), 1-13, 2022 | 46 | 2022 |
Classification, structural biology, and applications of mucin domain-targeting proteases DJ Shon, A Kuo, MJ Ferracane, SA Malaker Biochemical Journal 478 (8), 1585-1603, 2021 | 46 | 2021 |
Fluorocarbon modified low-molecular-weight polyethylenimine for siRNA delivery ME Johnson, J Shon, BM Guan, JP Patterson, NJ Oldenhuis, AC Eldredge, ... Bioconjugate chemistry 27 (8), 1784-1788, 2016 | 43 | 2016 |
Genome-wide, bidirectional CRISPR screens identify mucins as critical host factors modulating SARS-CoV-2 infection SB Biering, SA Sarnik, E Wang, JR Zengel, V Sathyan, X Nguyenla, ... BioRxiv, 2021.04. 22.440848, 2021 | 24 | 2021 |
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins K Pedram, DJ Shon, GS Tender, NR Mantuano, JJ Northey, KJ Metcalf, ... Nature Biotechnology, 1-11, 2023 | 23 | 2023 |
Small cell lung cancer cells express the late stage gBK tumor antigen: a possible immunotarget for the terminal disease NT Hoa, L Ge, RB Tajhya, C Beeton, AN Cornforth, A Abolhoda, ... American Journal of Translational Research 6 (3), 188, 2014 | 18 | 2014 |
Glycoproteomic landscape and structural dynamics of TIM family immune checkpoints enabled by mucinase SmE J Chongsaritsinsuk, AD Steigmeyer, KE Mahoney, MA Rosenfeld, ... Nature Communications 14 (1), 6169, 2023 | 14 | 2023 |
Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences DJ Shon, D Fernandez, NM Riley, MJ Ferracane, CR Bertozzi Journal of Biological Chemistry 298 (5), 2022 | 13 | 2022 |
Revealing the human mucinome SA Malaker, NM Riley, DJ Shon, K Pedram, V Krishnan, O Dorigo, ... bioRxiv, 2021.01. 27.428510, 2021 | 13 | 2021 |
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals K Pedram, NN Laqtom, DJ Shon, A Di Spiezio, NM Riley, P Saftig, ... Proceedings of the National Academy of Sciences 119 (39), e2117105119, 2022 | 8 | 2022 |
Using REMBRANDT to paint in the details of glioma biology: Applications for future immunotherapy AQ Dang, NT Hoa, L Ge, G Arismendi Morillo, B Paleo, EJ Gomez, ... Evolution of the molecular biology of brain tumors and the therapeutic …, 2013 | 8 | 2013 |
The microenvironment dictates glycocalyx construction and immune surveillance K Tharp, S Park, GA Timblin, A Richards, J Berg, N Twells, NMI Riley, ... bioRxiv, 2023.06. 23.546317, 2023 | 1 | 2023 |
Engineering Enzymes for Selective Detection and Degradation of Mucins DJ Shon Stanford University, 2023 | | 2023 |
Methods Employing Mucin-Specific Proteases CR Bertozzi, SA Malaker, K Pedram, D Shon US Patent App. 17/291,376, 2022 | | 2022 |
Novel “mucinomics” platform reveals molecular signatures of cancer in cellular systems and ovarian cancer patient ascites fluid S Malaker, N Riley, J Shon, K Pedram, C Bertozzi The FASEB Journal 35, 2021 | | 2021 |
Enzyme toolkit for selective enrichment and analysis of mucin-domain glycoproteins SA Malaker, J Shon, K Pedram, NM Riley, CR Bertozzi MOLECULAR & CELLULAR PROTEOMICS 18 (8), S42-S42, 2019 | | 2019 |
Cell-selective proteomic analysis of host-microbe interactions using Bio-orthogonal Noncanonical Amino Acid Tagging (BONCAT) S Stone, J Shon, A Khosravi, M Sweredoski, A Moradian, S Hess, ... | | 2017 |