| Direct evidence for increased hydroxyl radicals originating from superoxide in the failing myocardium T Ide, H Tsutsui, S Kinugawa, N Suematsu, S Hayashidani, K Ichikawa, ... Circulation research 86 (2), 152-157, 2000 | 516 | 2000 |
| Simultaneous molecular imaging of redox reactions monitored by Overhauser-enhanced MRI with 14N-and 15N-labeled nitroxyl radicals H Utsumi, K Yamada, K Ichikawa, K Sakai, Y Kinoshita, S Matsumoto, ... Proceedings of the National Academy of Sciences 103 (5), 1463-1468, 2006 | 171 | 2006 |
| Enhanced generation of reactive oxygen species in the limb skeletal muscles from a murine infarct model of heart failure H Tsutsui, T Ide, S Hayashidani, N Suematsu, T Shiomi, J Wen, ... Circulation 104 (2), 134-136, 2001 | 149 | 2001 |
| Esters of 5-carboxyl-5-methyl-1-pyrroline N-oxide: a family of spin traps for superoxide P Tsai, K Ichikawa, C Mailer, S Pou, HJ Halpern, BH Robinson, R Nielsen, ... The Journal of organic chemistry 68 (20), 7811-7817, 2003 | 92 | 2003 |
| A platform for designing hyperpolarized magnetic resonance chemical probes H Nonaka, R Hata, T Doura, T Nishihara, K Kumagai, M Akakabe, ... Nature communications 4 (1), 2411, 2013 | 91 | 2013 |
| In vivo toxicity and antitumor activity of mangosteen extract N Kosem, K Ichikawa, H Utsumi, P Moongkarndi Journal of natural medicines 67, 255-263, 2013 | 86 | 2013 |
| Influence of conformation on the EPR spectrum of 5, 5-dimethyl-1-hydroperoxy-1-pyrrolidinyloxyl: a spin trapped adduct of superoxide GM Rosen, A Beselman, P Tsai, S Pou, C Mailer, K Ichikawa, ... The Journal of Organic Chemistry 69 (4), 1321-1330, 2004 | 64 | 2004 |
| Quantitative analysis for the enhancement of hydroxyl radical generation by phenols during ozonation of water SK Han, K Ichikawa, H Utsumi Water Research 32 (11), 3261-3266, 1998 | 61 | 1998 |
| Dynamic nuclear polarization properties of nitroxyl radicals used in Overhauser-enhanced MRI for simultaneous molecular imaging AMF Benial, K Ichikawa, R Murugesan, K Yamada, H Utsumi Journal of magnetic resonance 182 (2), 273-282, 2006 | 52 | 2006 |
| Direct Monitoring of γ‐Glutamyl Transpeptidase Activity In Vivo Using a Hyperpolarized 13C‐Labeled Molecular Probe T Nishihara, HAI Yoshihara, H Nonaka, Y Takakusagi, F Hyodo, ... Angewandte Chemie International Edition 55 (36), 10626-10629, 2016 | 48 | 2016 |
| Design of a 15N Molecular Unit to Achieve Long Retention of Hyperpolarized Spin State H Nonaka, M Hirano, Y Imakura, Y Takakusagi, K Ichikawa, S Sando Scientific reports 7 (1), 40104, 2017 | 47 | 2017 |
| In vivo ESR measurements of free radical reactions in living mice H Utsumi, K Ichikawa, K Takeshita Toxicology letters 82, 561-565, 1995 | 43 | 1995 |
| Hyperpolarized [1-13C]-pyruvate magnetic resonance spectroscopic imaging of prostate cancer in vivo predicts efficacy of targeting the Warburg effect BT Scroggins, M Matsuo, AO White, K Saito, JP Munasinghe, C Sourbier, ... Clinical Cancer Research 24 (13), 3137-3148, 2018 | 41 | 2018 |
| Design of a hyperpolarized molecular probe for detection of aminopeptidase N activity R Hata, H Nonaka, Y Takakusagi, K Ichikawa, S Sando Angewandte Chemie International Edition 55 (5), 1765-1768, 2016 | 41 | 2016 |
| Advantageous application of a surface coil to EPR irradiation in Overhauser‐enhanced MRI S Matsumoto, K Yamada, H Hirata, K Yasukawa, F Hyodo, K Ichikawa, ... Magnetic Resonance in Medicine: An Official Journal of the International …, 2007 | 41 | 2007 |
| In vivo ESR measurements of free radical reactions in living mice H Utsumi, K Ichikawa, K Takeshita Toxicology letters 82, 561-565, 1995 | 37 | 1995 |
| Dendrimeric-containing nitronyl nitroxides as spin traps for nitric oxide: synthesis, kinetic, and stability studies GM Rosen, S Porasuphatana, P Tsai, NP Ambulos, VE Galtsev, ... Macromolecules 36 (4), 1021-1027, 2003 | 34 | 2003 |
| Design of a hyperpolarized 15 N NMR probe that induces a large chemical-shift change upon binding of calcium ions R Hata, H Nonaka, Y Takakusagi, K Ichikawa, S Sando Chemical communications 51 (61), 12290-12292, 2015 | 32 | 2015 |
| Design of a 13C Magnetic Resonance Probe Using a Deuterated Methoxy Group as a Long‐Lived Hyperpolarization Unit T Doura, R Hata, H Nonaka, K Ichikawa, S Sando Angewandte Chemie International Edition 40 (51), 10114-10117, 2012 | 31 | 2012 |
| Oxidative stress imaging in live animals with techniques based on electron paramagnetic resonance M Elas, K Ichikawa, HJ Halpern Radiation research 177 (4), 514-523, 2012 | 31 | 2012 |
