Kimal Rajapakshe
Kimal Rajapakshe
The University of Texas MD Anderson Cancer Center
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Cited by
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Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer
S Dasgupta, K Rajapakshe, B Zhu, BC Nikolai, P Yi, N Putluri, JM Choi, ...
Nature 556 (7700), 249-254, 2018
Novel BET protein proteolysis-targeting chimera exerts superior lethal activity than bromodomain inhibitor (BETi) against post-myeloproliferative neoplasm secondary (s) AML cells
DT Saenz, W Fiskus, Y Qian, T Manshouri, K Rajapakshe, K Raina, ...
Leukemia 31 (9), 1951-1961, 2017
Androgen receptor is the key transcriptional mediator of the tumor suppressor SPOP in prostate cancer
C Geng, K Rajapakshe, SS Shah, J Shou, VK Eedunuri, C Foley, ...
Cancer research 74 (19), 5631-5643, 2014
BET protein proteolysis targeting chimera (PROTAC) exerts potent lethal activity against mantle cell lymphoma cells
B Sun, W Fiskus, Y Qian, K Rajapakshe, K Raina, KG Coleman, AP Crew, ...
Leukemia 32 (2), 343-352, 2018
Critical role of cytosolic DNA and its sensing adaptor STING in aortic degeneration, dissection, and rupture
W Luo, Y Wang, L Zhang, P Ren, C Zhang, Y Li, AR Azares, M Zhang, ...
Circulation 141 (1), 42-66, 2020
Bempegaldesleukin selectively depletes intratumoral Tregs and potentiates T cell-mediated cancer therapy
M Sharma, H Khong, F Fa’ak, SE Bentebibel, LME Janssen, BC Chesson, ...
Nature communications 11 (1), 661, 2020
A pan-cancer analysis reveals high-frequency genetic alterations in mediators of signaling by the TGF-β superfamily
A Korkut, S Zaidi, RS Kanchi, S Rao, NR Gough, A Schultz, X Li, ...
Cell systems 7 (4), 422-437. e7, 2018
Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer
DA Bader, SM Hartig, V Putluri, C Foley, MP Hamilton, EA Smith, PK Saha, ...
Nature metabolism 1 (1), 70-85, 2019
Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates
V Chitsazzadeh, C Coarfa, JA Drummond, T Nguyen, A Joseph, ...
Nature communications 7 (1), 12601, 2016
GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex
B He, RB Lanz, W Fiskus, C Geng, P Yi, SM Hartig, K Rajapakshe, J Shou, ...
Proceedings of the National Academy of Sciences 111 (51), 18261-18266, 2014
IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo
A Venkatanarayan, P Raulji, W Norton, D Chakravarti, C Coarfa, X Su, ...
Nature 517 (7536), 626-630, 2015
Generation of an in vitro 3D PDAC stroma rich spheroid model
MJ Ware, V Keshishian, JJ Law, JC Ho, CA Favela, P Rees, B Smith, ...
Biomaterials 108, 129-142, 2016
Identification of a pan-cancer oncogenic microRNA superfamily anchored by a central core seed motif
MP Hamilton, K Rajapakshe, SM Hartig, B Reva, MD McLellan, ...
Nature communications 4 (1), 2730, 2013
Synergistic activity of BET protein antagonist-based combinations in mantle cell lymphoma cells sensitive or resistant to ibrutinib
B Sun, B Shah, W Fiskus, J Qi, K Rajapakshe, C Coarfa, L Li, ...
Blood, The Journal of the American Society of Hematology 126 (13), 1565-1574, 2015
The camKK2/camKIV relay is an essential regulator of hepatic cancer
F Lin, KL Marcelo, K Rajapakshe, C Coarfa, A Dean, N Wilganowski, ...
Hepatology 62 (2), 505-520, 2015
Transcriptional regulation of core autophagy and lysosomal genes by the androgen receptor promotes prostate cancer progression
AM Blessing, K Rajapakshe, L Reddy Bollu, Y Shi, MA White, AH Pham, ...
Autophagy 13 (3), 506-521, 2017
APOBEC mutation drives early-onset squamous cell carcinomas in recessive dystrophic epidermolysis bullosa
RJ Cho, LB Alexandrov, NY Den Breems, VS Atanasova, M Farshchian, ...
Science Translational Medicine 10 (455), eaas9668, 2018
Coactivator SRC-2–dependent metabolic reprogramming mediates prostate cancer survival and metastasis
S Dasgupta, N Putluri, W Long, B Zhang, J Wang, AK Kaushik, JM Arnold, ...
The Journal of clinical investigation 125 (3), 1174-1188, 2015
SPOP regulates prostate epithelial cell proliferation and promotes ubiquitination and turnover of c-MYC oncoprotein
C Geng, S Kaochar, M Li, K Rajapakshe, W Fiskus, J Dong, C Foley, ...
Oncogene 36 (33), 4767-4777, 2017
RUNX1-targeted therapy for AML expressing somatic or germline mutation in RUNX1
CP Mill, W Fiskus, CD DiNardo, Y Qian, K Raina, K Rajapakshe, D Perera, ...
Blood, The Journal of the American Society of Hematology 134 (1), 59-73, 2019
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