Mattia Mori
Mattia Mori
University of Siena, Department of Biotechnology, Chemistry and Pharmacy
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Gli1/DNA interaction is a druggable target for Hedgehog‐dependent tumors
P Infante, M Mori, R Alfonsi, F Ghirga, F Aiello, S Toscano, C Ingallina, ...
The EMBO journal 34 (2), 200-217, 2015
Targeting GLI factors to inhibit the Hedgehog pathway
P Infante, R Alfonsi, B Botta, M Mori, L Di Marcotullio
Trends in pharmacological sciences 36 (8), 547-558, 2015
Targeting the RdRp of emerging RNA viruses: the structure-based drug design challenge
F Picarazzi, I Vicenti, F Saladini, M Zazzi, M Mori
Molecules 25 (23), 5695, 2020
Nucleocapsid protein: a desirable target for future therapies against HIV-1
M Mori, L Kovalenko, S Lyonnais, D Antaki, BE Torbett, M Botta, ...
The Future of HIV-1 Therapeutics: Resistance Is Futile?, 53-92, 2015
A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy …
B Cevatemre, M Erkısa, N Aztopal, D Karakas, P Alper, C Tsimplouli, ...
Pharmacological Research 129, 500-514, 2018
Discovery of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (PtpB) Inhibitors from Natural Products
A Mascarello, M Mori, LD Chiaradia-Delatorre, ACO Menegatti, ...
PloS one 8 (10), e77081, 2013
Structure, function, involvement in diseases and targeting of 14-3-3 proteins: an update
Y Cau, D Valensin, M Mori, S Draghi, M Botta
Current medicinal chemistry 25 (1), 5-21, 2018
Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype
P Infante, R Alfonsi, C Ingallina, D Quaglio, F Ghirga, I D'acquarica, ...
Cell death & disease 7 (9), e2376-e2376, 2016
Repurposing drugs for the management of COVID-19
J Cusinato, Y Cau, AM Calvani, M Mori
Expert opinion on therapeutic patents 31 (4), 295-307, 2021
Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis
P Infante, R Faedda, F Bernardi, F Bufalieri, L Lospinoso Severini, ...
Nature communications 9 (1), 976, 2018
Nucleotide sequence of rat liver aldolase B messenger RNA.
K Tsutsumi, T Mukai, R Tsutsumi, M Mori, M Daimon, T Tanaka, H Yatsuki, ...
Journal of Biological Chemistry 259 (23), 14572-14575, 1984
Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia
M Mori, L Tottone, D Quaglio, N Zhdanovskaya, C Ingallina, M Fusto, ...
Scientific Reports 7 (1), 2213, 2017
Computational techniques are valuable tools for the discovery of protein–protein interaction inhibitors: the 14-3-3σ case
V Corradi, M Mancini, MA Santucci, T Carlomagno, D Sanfelice, M Mori, ...
Bioorganic & medicinal chemistry letters 21 (22), 6867-6871, 2011
Molecular dynamics and DFT study on HIV-1 nucleocapsid protein-7 in complex with viral genome
M Mori, U Dietrich, F Manetti, M Botta
Journal of chemical information and modeling 50 (4), 638-650, 2010
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61
A Calcaterra, V Iovine, B Botta, D Quaglio, I D’Acquarica, A Ciogli, ...
Journal of enzyme inhibition and medicinal chemistry 33 (1), 349-358, 2018
2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo [3, 4-d] pyrimidines Src-Abl dual inhibitors
E Dreassi, AT Zizzari, M Mori, I Filippi, A Belfiore, A Naldini, F Carraro, ...
European journal of medicinal chemistry 45 (12), 5958-5964, 2010
A smo/gli multitarget hedgehog pathway inhibitor impairs tumor growth
L Lospinoso Severini, D Quaglio, I Basili, F Ghirga, F Bufalieri, ...
Cancers 11 (10), 1518, 2019
A deadly spillover: SARS-CoV-2 outbreak
M Mori, C Capasso, F Carta, WA Donald, CT Supuran
Expert Opinion on Therapeutic Patents 30 (7), 481-485, 2020
Nigritanine as a New Potential Antimicrobial Alkaloid for the Treatment of Staphylococcus aureus-Induced Infections
B Casciaro, A Calcaterra, F Cappiello, M Mori, MR Loffredo, F Ghirga, ...
Toxins 11 (9), 511, 2019
Naturally occurring Diels-Alder-type adducts from Morus nigra as potent inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase B
A Mascarello, ACO Menegatti, A Calcaterra, PGA Martins, ...
European journal of medicinal chemistry 144, 277-288, 2018
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