Gli1/DNA interaction is a druggable target for Hedgehog‐dependent tumors P Infante, M Mori, R Alfonsi, F Ghirga, F Aiello, S Toscano, C Ingallina, ... The EMBO journal 34 (2), 200-217, 2015 | 190 | 2015 |
Targeting GLI factors to inhibit the Hedgehog pathway P Infante, R Alfonsi, B Botta, M Mori, L Di Marcotullio Trends in pharmacological sciences 36 (8), 547-558, 2015 | 120 | 2015 |
Targeting the RdRp of emerging RNA viruses: the structure-based drug design challenge F Picarazzi, I Vicenti, F Saladini, M Zazzi, M Mori Molecules 25 (23), 5695, 2020 | 87 | 2020 |
A promising natural product, pristimerin, results in cytotoxicity against breast cancer stem cells in vitro and xenografts in vivo through apoptosis and an incomplete autopaghy … B Cevatemre, M Erkısa, N Aztopal, D Karakas, P Alper, C Tsimplouli, ... Pharmacological Research 129, 500-514, 2018 | 75 | 2018 |
Nucleocapsid protein: a desirable target for future therapies against HIV-1 M Mori, L Kovalenko, S Lyonnais, D Antaki, BE Torbett, M Botta, ... The Future of HIV-1 Therapeutics: Resistance Is Futile?, 53-92, 2015 | 75 | 2015 |
Structure, function, involvement in diseases and targeting of 14-3-3 proteins: an update Y Cau, D Valensin, M Mori, S Draghi, M Botta Current medicinal chemistry 25 (1), 5-21, 2018 | 74 | 2018 |
Repurposing drugs for the management of COVID-19 J Cusinato, Y Cau, AM Calvani, M Mori Expert opinion on therapeutic patents 31 (4), 295-307, 2021 | 70 | 2021 |
Discovery of Mycobacterium tuberculosis Protein Tyrosine Phosphatase B (PtpB) Inhibitors from Natural Products A Mascarello, M Mori, LD Chiaradia-Delatorre, ACO Menegatti, ... PloS one 8 (10), e77081, 2013 | 67 | 2013 |
Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype P Infante, R Alfonsi, C Ingallina, D Quaglio, F Ghirga, I D'acquarica, ... Cell death & disease 7 (9), e2376-e2376, 2016 | 66 | 2016 |
Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis P Infante, R Faedda, F Bernardi, F Bufalieri, L Lospinoso Severini, ... Nature communications 9 (1), 976, 2018 | 64 | 2018 |
Nucleotide sequence of rat liver aldolase B messenger RNA. K Tsutsumi, T Mukai, R Tsutsumi, M Mori, M Daimon, T Tanaka, H Yatsuki, ... Journal of Biological Chemistry 259 (23), 14572-14575, 1984 | 62 | 1984 |
Computational techniques are valuable tools for the discovery of protein–protein interaction inhibitors: the 14-3-3σ case V Corradi, M Mancini, MA Santucci, T Carlomagno, D Sanfelice, M Mori, ... Bioorganic & medicinal chemistry letters 21 (22), 6867-6871, 2011 | 60 | 2011 |
Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61 A Calcaterra, V Iovine, B Botta, D Quaglio, I D’Acquarica, A Ciogli, ... Journal of enzyme inhibition and medicinal chemistry 33 (1), 349-358, 2018 | 58 | 2018 |
Imidazo[1,2-a]pyridine Derivatives as Aldehyde Dehydrogenase Inhibitors: Novel Chemotypes to Target Glioblastoma Stem Cells L Quattrini, ELM Gelardi, V Coviello, S Sartini, DM Ferraris, M Mori, ... Journal of Medicinal Chemistry 63 (9), 4603-4616, 2020 | 55 | 2020 |
Identification of a novel chalcone derivative that inhibits Notch signaling in T-cell acute lymphoblastic leukemia M Mori, L Tottone, D Quaglio, N Zhdanovskaya, C Ingallina, M Fusto, ... Scientific Reports 7 (1), 2213, 2017 | 54 | 2017 |
Molecular dynamics and DFT study on HIV-1 nucleocapsid protein-7 in complex with viral genome M Mori, U Dietrich, F Manetti, M Botta Journal of chemical information and modeling 50 (4), 638-650, 2010 | 51 | 2010 |
2-Hydroxypropyl-β-cyclodextrin strongly improves water solubility and anti-proliferative activity of pyrazolo [3, 4-d] pyrimidines Src-Abl dual inhibitors E Dreassi, AT Zizzari, M Mori, I Filippi, A Belfiore, A Naldini, F Carraro, ... European journal of medicinal chemistry 45 (12), 5958-5964, 2010 | 50 | 2010 |
SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells Q Hammer, J Dunst, W Christ, F Picarazzi, M Wendorff, P Momayyezi, ... Cell reports 38 (10), 2022 | 49 | 2022 |
Nigritanine as a New Potential Antimicrobial Alkaloid for the Treatment of Staphylococcus aureus-Induced Infections B Casciaro, A Calcaterra, F Cappiello, M Mori, MR Loffredo, F Ghirga, ... Toxins 11 (9), 511, 2019 | 49 | 2019 |
Hedgehog signaling pathway inhibitors: an updated patent review (2015–present) D Quaglio, P Infante, L Di Marcotullio, B Botta, M Mori Expert Opinion on Therapeutic Patents 30 (4), 235-250, 2020 | 48 | 2020 |