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Kelly Whelan
Kelly Whelan
Temple University Lewis Katz School of Medicine
Dirección de correo verificada de temple.edu
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Histone sumoylation is a negative regulator in Saccharomyces cerevisiae and shows dynamic interplay with positive-acting histone modifications
D Nathan, K Ingvarsdottir, DE Sterner, GR Bylebyl, M Dokmanovic, ...
Genes & development 20 (8), 966-976, 2006
4802006
H2B ubiquitylation acts as a barrier to Ctk1 nucleosomal recruitment prior to removal by Ubp8 within a SAGA-related complex
A Wyce, T Xiao, KA Whelan, C Kosman, W Walter, D Eick, TR Hughes, ...
Molecular cell 27 (2), 275-288, 2007
2502007
Interplay between Notch1 and Notch3 promotes EMT and tumor initiation in squamous cell carcinoma
M Natsuizaka, KA Whelan, S Kagawa, K Tanaka, V Giroux, ...
Nature communications 8 (1), 1758, 2017
1922017
Clinical and translational advances in esophageal squamous cell carcinoma
ZW Reichenbach, MG Murray, R Saxena, D Farkas, EG Karassik, ...
Advances in cancer research 144, 95-135, 2019
1492019
In vivo modulation of O-GlcNAc levels regulates hippocampal synaptic plasticity through interplay with phosphorylation
MK Tallent, N Varghis, Y Skorobogatko, L Hernandez-Cuebas, K Whelan, ...
Journal of biological chemistry 284 (1), 174-181, 2009
1482009
Trimethylation of histone H3 lysine 4 by Set1 in the lytic infection of human herpes simplex virus 1
J Huang, JR Kent, B Placek, KA Whelan, CM Hollow, PY Zeng, NW Fraser, ...
Journal of virology 80 (12), 5740-5746, 2006
1292006
Three-dimensional organoids reveal therapy resistance of esophageal and oropharyngeal squamous cell carcinoma cells
T Kijima, H Nakagawa, M Shimonosono, PM Chandramouleeswaran, ...
Cellular and molecular gastroenterology and hepatology 7 (1), 73-91, 2019
1212019
ErbB2 requires integrin α5 for anoikis resistance via Src regulation of receptor activity in human mammary epithelial cells
KK Haenssen, SA Caldwell, KS Shahriari, SRE Jackson, KA Whelan, ...
Journal of cell science 123 (8), 1373-1382, 2010
1202010
The esophageal organoid system reveals functional interplay between notch and cytokines in reactive epithelial changes
Y Kasagi, PM Chandramouleeswaran, KA Whelan, K Tanaka, V Giroux, ...
Cellular and molecular gastroenterology and hepatology 5 (3), 333-352, 2018
1002018
Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration
V Giroux, AA Lento, M Islam, JR Pitarresi, A Kharbanda, KE Hamilton, ...
The Journal of clinical investigation 127 (6), 2378-2391, 2017
1002017
Disruption of cytochrome c oxidase function induces the Warburg effect and metabolic reprogramming
S Srinivasan, M Guha, DW Dong, KA Whelan, G Ruthel, Y Uchikado, ...
Oncogene 35 (12), 1585-1595, 2016
972016
IGFBP3 promotes esophageal cancer growth by suppressing oxidative stress in hypoxic tumor microenvironment
M Natsuizaka, H Kinugasa, S Kagawa, KA Whelan, S Naganuma, ...
American journal of cancer research 4 (1), 29, 2014
922014
Mitochondrial SOD2 regulates epithelial–mesenchymal transition and cell populations defined by differential CD44 expression
H Kinugasa, KA Whelan, K Tanaka, M Natsuizaka, A Long, A Guo, ...
Oncogene 34 (41), 5229-5239, 2015
862015
Fibroblast growth factor-2–mediated FGFR/Erk signaling supports maintenance of cancer stem-like cells in esophageal squamous cell carcinoma
O Maehara, G Suda, M Natsuizaka, S Ohnishi, Y Komatsu, F Sato, ...
Carcinogenesis 38 (11), 1073-1083, 2017
852017
Autophagy supports generation of cells with high CD44 expression via modulation of oxidative stress and Parkin-mediated mitochondrial clearance
KA Whelan, PM Chandramouleeswaran, K Tanaka, M Natsuizaka, ...
Oncogene 36 (34), 4843-4858, 2017
812017
The oncogene HER2/neu (ERBB2) requires the hypoxia-inducible factor HIF-1 for mammary tumor growth and anoikis resistance
KA Whelan, LP Schwab, SV Karakashev, L Franchetti, GJ Johannes, ...
Journal of Biological Chemistry 288 (22), 15865-15877, 2013
812013
WNT10A promotes an invasive and self-renewing phenotype in esophageal squamous cell carcinoma
A Long, V Giroux, KA Whelan, KE Hamilton, MP Tétreault, K Tanaka, ...
Carcinogenesis 36 (5), 598-606, 2015
762015
Hypoxia suppression of Bim and Bmf blocks anoikis and luminal clearing during mammary morphogenesis
KA Whelan, SA Caldwell, KS Shahriari, SRE Jackson, LD Franchetti, ...
Molecular biology of the cell 21 (22), 3829-3837, 2010
752010
Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities
S Kagawa, M Natsuizaka, KA Whelan, N Facompre, S Naganuma, ...
Oncogene 34 (18), 2347-2359, 2015
692015
Esophageal 3D culture systems as modeling tools in esophageal epithelial pathobiology and personalized medicine
KA Whelan, AB Muir, H Nakagawa
Cellular and molecular gastroenterology and hepatology 5 (4), 461-478, 2018
642018
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20