Jacob Stewart-Ornstein
Jacob Stewart-Ornstein
University of Pittsburgh, Dept. of Comp. and Syst. Biology
Verified email at
Cited by
Cited by
A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress
O Brandman, J Stewart-Ornstein, D Wong, A Larson, CC Williams, GW Li, ...
Cell 151 (5), 1042-1054, 2012
A comprehensive strategy enabling high-resolution functional analysis of the yeast genome
DK Breslow, DM Cameron, SR Collins, M Schuldiner, J Stewart-Ornstein, ...
Nature methods 5 (8), 711-718, 2008
In silico feedback for in vivo regulation of a gene expression circuit
A Milias-Argeitis, S Summers, J Stewart-Ornstein, I Zuleta, D Pincus, ...
Nature biotechnology 29 (12), 1114-1116, 2011
Cellular noise regulons underlie fluctuations in Saccharomyces cerevisiae
J Stewart-Ornstein, JS Weissman, H El-Samad
Molecular cell 45 (4), 483-493, 2012
Fluctuations in p53 signaling allow escape from cell-cycle arrest
J Reyes, JY Chen, J Stewart-Ornstein, KW Karhohs, CS Mock, G Lahav
Molecular cell 71 (4), 581-591. e5, 2018
p53 pulses lead to distinct patterns of gene expression albeit similar DNA-binding dynamics
A Hafner, J Stewart-Ornstein, JE Purvis, WC Forrester, ML Bulyk, G Lahav
Nature structural & molecular biology 24 (10), 840-847, 2017
Using intrinsic X-ray absorption spectral differences to identify and map peptides and proteins
J Stewart-Ornstein, AP Hitchcock, D Hernández Cruz, P Henklein, ...
The Journal of Physical Chemistry B 111 (26), 7691-7699, 2007
p53 dynamics in response to DNA damage vary across cell lines and are shaped by efficiency of DNA repair and activity of the kinase ATM
J Stewart-Ornstein, G Lahav
Science signaling 10 (476), eaah6671, 2017
Dynamics of CDKN1A in single cells defined by an endogenous fluorescent tagging toolkit
J Stewart-Ornstein, G Lahav
Cell reports 14 (7), 1800-1811, 2016
In situ spatial and time-resolved studies of electrochemical reactions by scanning transmission X-ray microscopy
D Guay, J Stewart-Ornstein, X Zhang, AP Hitchcock
Analytical chemistry 77 (11), 3479-3487, 2005
Msn2 coordinates a stoichiometric gene expression program
J Stewart-Ornstein, C Nelson, J DeRisi, JS Weissman, H El-Samad
Current Biology 23 (23), 2336-2345, 2013
Conservation and divergence of p53 oscillation dynamics across species
J Stewart-Ornstein, HWJ Cheng, G Lahav
Cell systems 5 (4), 410-417. e4, 2017
Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening
RP Barnes, M de Rosa, SA Thosar, AC Detwiler, V Roginskaya, ...
Nature structural & molecular biology 29 (7), 639-652, 2022
p53 dynamics vary between tissues and are linked with radiation sensitivity
J Stewart-Ornstein, Y Iwamoto, MA Miller, MA Prytyskach, S Ferretti, ...
Nature Communications 12 (1), 898, 2021
Optogenetic control reveals differential promoter interpretation of transcription factor nuclear translocation dynamics
SY Chen, LC Osimiri, M Chevalier, LJ Bugaj, TH Nguyen, RA Greenstein, ...
Cell systems 11 (4), 336-353. e24, 2020
The effects of proliferation status and cell cycle phase on the responses of single cells to chemotherapy
AE Granada, A Jiménez, J Stewart-Ornstein, N Blüthgen, S Reber, ...
Molecular biology of the cell 31 (8), 845-857, 2020
Quantifying the central dogma in the p53 pathway in live single cells
A Hafner, J Reyes, J Stewart-Ornstein, M Tsabar, A Jambhekar, G Lahav
Cell systems 10 (6), 495-505. e4, 2020
Model-guided optogenetic study of PKA signaling in budding yeast
J Stewart-Ornstein, S Chen, R Bhatnagar, JS Weissman, H El-Samad
Molecular Biology of the cell 28 (1), 221-227, 2017
Building robust functionality in synthetic circuits using engineered feedback regulation
S Chen, P Harrigan, B Heineike, J Stewart-Ornstein, H El-Samad
Current opinion in biotechnology 24 (4), 790-796, 2013
RNA-seq reveals novel mechanistic targets of withaferin A in prostate cancer cells
SH Kim, ER Hahm, KB Singh, S Shiva, J Stewart-Ornstein, SV Singh
Carcinogenesis 41 (6), 778-789, 2020
The system can't perform the operation now. Try again later.
Articles 1–20