Redox-and non-redox-metal-induced formation of free radicals and their role in human disease M Valko, K Jomova, CJ Rhodes, K Kuča, K Musílek Archives of toxicology 90, 1-37, 2016 | 1074 | 2016 |
Structural requirements of acetylcholinesterase reactivators K Kuca, D Jun, K Musilek Mini reviews in medicinal chemistry 6 (3), 269-277, 2006 | 282 | 2006 |
Design, evaluation and structure—Activity relationship studies of the AChE reactivators against organophosphorus pesticides K Musilek, M Dolezal, F Gunn‐Moore, K Kuca Medicinal research reviews 31 (4), 548-575, 2011 | 154 | 2011 |
Design of a Potent Reactivator of Tabun-Inhibited AcetylcholinesteraseSynthesis and Evaluation of (E)-1-(4-Carbamoylpyridinium)-4-(4 … K Musilek, D Jun, J Cabal, J Kassa, F Gunn-Moore, K Kuca Journal of medicinal chemistry 50 (22), 5514-5518, 2007 | 140 | 2007 |
A resurrection of 7-MEOTA: a comparison with tacrine O Soukup, D Jun, J Zdarova-Karasova, J Patocka, K Musilek, J Korabecny, ... Current Alzheimer Research 10 (8), 893-906, 2013 | 128 | 2013 |
SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides L Gorecki, J Korabecny, K Musilek, D Malinak, E Nepovimova, R Dolezal, ... Archives of toxicology 90, 2831-2859, 2016 | 116 | 2016 |
Progress of biosensors based on cholinesterase inhibition M Pohanka, K Musilek, K Kuca Current medicinal chemistry 16 (14), 1790-1798, 2009 | 98 | 2009 |
An evaluation of therapeutic and reactivating effects of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice J Kassa, J Karasova, K Musilek, K Kuca Toxicology 243 (3), 311-316, 2008 | 98 | 2008 |
7-MEOTA–donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies J Korabecny, R Dolezal, P Cabelova, A Horova, E Hruba, J Ricny, ... European journal of medicinal chemistry 82, 426-438, 2014 | 96 | 2014 |
Progress in synthesis of new acetylcholinesterase reactivators during the period 1990-2004 K Musilek, K Kuca, D Jun, M Dolezal Current Organic Chemistry 11 (2), 229-238, 2007 | 96 | 2007 |
7-Methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors in Alzheimer’s disease treatment—synthesis, biological evaluation and molecular modeling studies K Spilovska, J Korabecny, J Kral, A Horova, K Musilek, O Soukup, ... Molecules 18 (2), 2397-2418, 2013 | 95 | 2013 |
The progress in the cholinesterase quantification methods O Holas, K Musilek, M Pohanka, K Kuca Expert opinion on drug discovery 7 (12), 1207-1223, 2012 | 93 | 2012 |
Synthesis and in vitro evaluation of N-alkyl-7-methoxytacrine hydrochlorides as potential cholinesterase inhibitors in Alzheimer disease J Korabecny, K Musilek, O Holas, J Binder, F Zemek, J Marek, M Pohanka, ... Bioorganic & medicinal chemistry letters 20 (20), 6093-6095, 2010 | 90 | 2010 |
Evaluation of oxime K203 as antidote in tabun poisoning Z Kovarik, A Lucić Vrdoljak, S Berend, M Katalinić, K Kuča, K Musilek, ... Arhiv za higijenu rada i toksikologiju 60 (1), 19-26, 2009 | 86 | 2009 |
Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited … K Musilek, K Kuca, D Jun, V Dohnal, M Dolezal Bioorganic & medicinal chemistry letters 16 (3), 622-627, 2006 | 86 | 2006 |
Development and structural modifications of cholinesterase reactivators against chemical warfare agents in last decade: a review R Sharma, B Gupta, N Singh, JR Acharya, K Musilek, K Kuca, ... Mini Reviews in Medicinal Chemistry 15 (1), 58-72, 2015 | 84 | 2015 |
Synthesis of a novel series of bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase K Musilek, K Kuca, D Jun, V Dohnal, M Dolezal Journal of Enzyme Inhibition and Medicinal Chemistry 20 (5), 409-415, 2005 | 77 | 2005 |
An update on T-2 toxin and its modified forms: Metabolism, immunotoxicity mechanism, and human exposure assessment Q Wu, Z Qin, K Kuca, L You, Y Zhao, A Liu, K Musilek, Z Chrienova, ... Archives of Toxicology 94, 3645-3669, 2020 | 76 | 2020 |
Synthesis of monooxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun- and … K Musilek, O Holas, K Kuca, D Jun, V Dohnal, V Opletalova, M Dolezal Journal of enzyme inhibition and medicinal chemistry 23 (1), 70-76, 2008 | 75 | 2008 |
Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker—Preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase K Musilek, O Holas, D Jun, V Dohnal, F Gunn-Moore, V Opletalova, ... Bioorganic & medicinal chemistry 15 (21), 6733-6741, 2007 | 73 | 2007 |