Kamil Musílek
Kamil Musílek
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Redox-and non-redox-metal-induced formation of free radicals and their role in human disease
M Valko, K Jomova, CJ Rhodes, K Kuča, K Musílek
Archives of toxicology 90 (1), 1-37, 2016
4102016
Structural requirements of acetylcholinesterase reactivators
K Kuca, D Jun, K Musilek
Mini reviews in medicinal chemistry 6 (3), 269-277, 2006
2502006
Design of a Potent Reactivator of Tabun-Inhibited AcetylcholinesteraseSynthesis and Evaluation of (E)-1-(4-Carbamoylpyridinium)-4-(4 …
K Musilek, D Jun, J Cabal, J Kassa, F Gunn-Moore, K Kuca
Journal of medicinal chemistry 50 (22), 5514-5518, 2007
1222007
Design, evaluation and structure—Activity relationship studies of the AChE reactivators against organophosphorus pesticides
K Musilek, M Dolezal, F Gunn‐Moore, K Kuca
Medicinal research reviews 31 (4), 548-575, 2011
1202011
A resurrection of 7-MEOTA: a comparison with tacrine
O Soukup, D Jun, J Zdarova-Karasova, J Patocka, K Musilek, J Korabecny, ...
Current Alzheimer Research 10 (8), 893-906, 2013
922013
An evaluation of therapeutic and reactivating effects of newly developed oximes (K156, K203) and commonly used oximes (obidoxime, trimedoxime, HI-6) in tabun-poisoned rats and mice
J Kassa, J Karasova, K Musilek, K Kuca
Toxicology 243 (3), 311-316, 2008
892008
Progress in synthesis of new acetylcholinesterase reactivators during the period 1990-2004
K Musilek, K Kuca, D Jun, M Dolezal
Current Organic Chemistry 11 (2), 229-238, 2007
882007
Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited …
K Musilek, K Kuca, D Jun, V Dohnal, M Dolezal
Bioorganic & medicinal chemistry letters 16 (3), 622-627, 2006
802006
Progress of biosensors based on cholinesterase inhibition
M Pohanka, K Musilek, K Kuca
Current medicinal chemistry 16 (14), 1790-1798, 2009
782009
Evaluation of oxime K203 as antidote in tabun poisoning
Z Kovarik, A Vrdoljak, S Berend, M Katalinić, K Kuča, K Musilek, B Radić
Archives of Industrial Hygiene and Toxicology 60 (1), 19-26, 2009
742009
Synthesis and in vitro evaluation of N-alkyl-7-methoxytacrine hydrochlorides as potential cholinesterase inhibitors in Alzheimer disease
J Korabecny, K Musilek, O Holas, J Binder, F Zemek, J Marek, M Pohanka, ...
Bioorganic & medicinal chemistry letters 20 (20), 6093-6095, 2010
722010
Synthesis of a novel series of bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase
K Musilek, K Kuca, D Jun, V Dohnal, M Dolezal
Journal of Enzyme Inhibition and Medicinal Chemistry 20 (5), 409-415, 2005
692005
7-Methoxytacrine-adamantylamine heterodimers as cholinesterase inhibitors in Alzheimer’s disease treatment—synthesis, biological evaluation and molecular modeling studies
K Spilovska, J Korabecny, J Kral, A Horova, K Musilek, O Soukup, ...
Molecules 18 (2), 2397-2418, 2013
682013
7-MEOTA–donepezil like compounds as cholinesterase inhibitors: Synthesis, pharmacological evaluation, molecular modeling and QSAR studies
J Korabecny, R Dolezal, P Cabelova, A Horova, E Hruba, J Ricny, ...
European journal of medicinal chemistry 82, 426-438, 2014
662014
Monooxime reactivators of acetylcholinesterase with (E)-but-2-ene linker—Preparation and reactivation of tabun- and paraoxon-inhibited acetylcholinesterase
K Musilek, O Holas, D Jun, V Dohnal, F Gunn-Moore, V Opletalova, ...
Bioorganic & medicinal chemistry 15 (21), 6733-6741, 2007
652007
SAR study to find optimal cholinesterase reactivator against organophosphorous nerve agents and pesticides
L Gorecki, J Korabecny, K Musilek, D Malinak, E Nepovimova, R Dolezal, ...
Archives of toxicology 90 (12), 2831-2859, 2016
642016
Synthesis of monooxime-monocarbamoyl bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against tabun- and …
K Musilek, O Holas, K Kuca, D Jun, V Dohnal, V Opletalova, M Dolezal
Journal of enzyme inhibition and medicinal chemistry 23 (1), 70-76, 2008
642008
Effective bisquaternary reactivators of tabun‐inhibited AChE
K Kuca, J Cabal, K Musilek, D Jun, J Bajgar
Journal of Applied Toxicology: An International Journal 25 (6), 491-495, 2005
582005
Efficient Preparation of Organic Substrate− RNA Conjugates via in Vitro Transcription
R Fiammengo, K Musílek, A Jäschke
Journal of the American Chemical Society 127 (25), 9271-9276, 2005
582005
Synthesis of a novel series of non-symmetrical bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against tabun and paraoxon …
K Musilek, O Holas, K Kuca, D Jun, V Dohnal, M Dolezal
Journal of enzyme inhibition and medicinal chemistry 22 (4), 425-432, 2007
572007
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