| Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling I Al Ghouleh, NKH Khoo, UG Knaus, KK Griendling, RM Touyz, ... Free Radical Biology and Medicine 51 (7), 1271-1288, 2011 | 282 | 2011 |
| Nox2 B-loop peptide, Nox2ds, specifically inhibits the NADPH oxidase Nox2 G Csányi, E Cifuentes-Pagano, I Al Ghouleh, DJ Ranayhossaini, L Egaña, ... Free Radical Biology and Medicine 51 (6), 1116-1125, 2011 | 143 | 2011 |
| Thrombospondin-1 regulates blood flow via CD47 receptor–mediated activation of NADPH oxidase 1 G Csányi, M Yao, AI Rodríguez, IA Ghouleh, M Sharifi-Sanjani, ... Arteriosclerosis, thrombosis, and vascular biology 32 (12), 2966-2973, 2012 | 117 | 2012 |
| Aquaporin 1, Nox1, and Ask1 mediate oxidant-induced smooth muscle cell hypertrophy I Al Ghouleh, G Frazziano, AI Rodriguez, G Csanyi, S Maniar, CM St Croix, ... Cardiovascular Research 97 (1), 134-142, 2013 | 90 | 2013 |
| The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1 DN Meijles, S Sahoo, I Al Ghouleh, JH Amaral, R Bienes-Martinez, ... Science signaling 10 (501), eaaj1784, 2017 | 72 | 2017 |
| Nox-derived ROS are acutely activated in pressure overload pulmonary hypertension: indications for a seminal role for mitochondrial Nox4 G Frazziano, I Al Ghouleh, J Baust, S Shiva, HC Champion, PJ Pagano American Journal of Physiology-Heart and Circulatory Physiology 306 (2 …, 2014 | 67 | 2014 |
| MEF2C-MYOCD and leiomodin1 suppression by miRNA-214 promotes smooth muscle cell phenotype switching in pulmonary arterial hypertension S Sahoo, DN Meijles, I Al Ghouleh, M Tandon, E Cifuentes-Pagano, ... PLoS One 11 (5), e0153780, 2016 | 64 | 2016 |
| Endothelial-to-mesenchymal transition in pulmonary arterial hypertension A Gorelova, M Berman, I Al Ghouleh Antioxidants & redox signaling 34 (12), 891-914, 2021 | 62 | 2021 |
| Focus on early events: pathogenesis of pulmonary arterial hypertension development O Rafikova, I Al Ghouleh, R Rafikov Antioxidants & redox signaling 31 (13), 933-953, 2019 | 60 | 2019 |
| Endothelial Nox1 oxidase assembly in human pulmonary arterial hypertension; driver of Gremlin1-mediated proliferation IA Ghouleh, S Sahoo, DN Meijles, JH Amaral, DS de Jesus, J Sembrat, ... Clinical Science 131 (15), 2019-2035, 2017 | 52 | 2017 |
| Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitors E Cifuentes-Pagano, J Saha, G Csányi, I Al Ghouleh, S Sahoo, ... Medchemcomm 4 (7), 1085-1092, 2013 | 42 | 2013 |
| Adventitia-derived hydrogen peroxide impairs relaxation of the rat carotid artery via smooth muscle cell p38 mitogen-activated protein kinase T Cascino, G Csanyi, I Al Ghouleh, AC Montezano, RM Touyz, ... Antioxidants & redox signaling 15 (6), 1507-1515, 2011 | 39 | 2011 |
| Binding of EBP50 to Nox organizing subunit p47phox is pivotal to cellular reactive species generation and altered vascular phenotype I Al Ghouleh, DN Meijles, S Mutchler, Q Zhang, S Sahoo, A Gorelova, ... Proceedings of the National Academy of Sciences 113 (36), E5308-E5317, 2016 | 35 | 2016 |
| CD47 and Nox1 mediate dynamic fluid-phase macropinocytosis of native LDL G Csányi, DM Feck, P Ghoshal, B Singla, H Lin, S Nagarajan, DN Meijles, ... Antioxidants & Redox Signaling 26 (16), 886-901, 2017 | 32 | 2017 |
| Nicotinamide adenine dinucleotide phosphate (reduced form) oxidase is important for LPS-induced endothelial cell activation I Al Ghouleh, S Magder Shock 29 (5), 553-559, 2008 | 20 | 2008 |
| Computational repurposing of therapeutic small molecules from cancer to pulmonary hypertension V Negi, J Yang, G Speyer, A Pulgarin, A Handen, J Zhao, YY Tai, Y Tang, ... Science advances 7 (43), eabh3794, 2021 | 18 | 2021 |
| Yes-associated protein (Yap) is up-regulated in heart failure and promotes cardiac fibroblast proliferation M Sharifi-Sanjani, M Berman, D Goncharov, M Alhamaydeh, TG Avolio, ... International journal of molecular sciences 22 (11), 6164, 2021 | 15 | 2021 |
| Proteomic analysis identifies an NADPH oxidase 1 (Nox1)-mediated role for actin-related protein 2/3 complex subunit 2 (ARPC2) in promoting smooth muscle cell migration I Al Ghouleh, A Rodríguez, PJ Pagano, G Csányi International journal of molecular sciences 14 (10), 20220-20235, 2013 | 15 | 2013 |
| NADPH Oxidase–Derived Superoxide Destabilizes Lipopolysaccharide-Induced Interleukin 8 mRNA Via p38, Extracellular Signal–Regulated Kinase Mitogen-Activated Protein Kinase, and … I Al Ghouleh, S Magder Shock 37 (4), 433-440, 2012 | 11 | 2012 |
| Preservation of Renal Blood Flow by the Antioxidant EUK-134 in LPS-Treated Pigs S Magder, DG Parthenis, I Al Ghouleh International journal of molecular sciences 16 (4), 6801-6817, 2015 | 7 | 2015 |
Patrick PaganoProfessor of Pharmacology & Chemical Biology, PI in the Vascular Medicine InstituteDirección de correo verificada de pitt.edu
