| Tracking changes in SARS-CoV-2 spike: evidence that D614G increases infectivity of the COVID-19 virus B Korber, WM Fischer, S Gnanakaran, H Yoon, J Theiler, W Abfalterer, ... Cell 182 (4), 812-827. e19, 2020 | 4511 | 2020 |
| Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection JM Dan, J Mateus, Y Kato, KM Hastie, ED Yu, CE Faliti, A Grifoni, ... Science 371 (6529), eabf4063, 2021 | 3099 | 2021 |
| Antigen-specific adaptive immunity to SARS-CoV-2 in acute COVID-19 and associations with age and disease severity CR Moderbacher, SI Ramirez, JM Dan, A Grifoni, KM Hastie, D Weiskopf, ... Cell 183 (4), 996-1012. e19, 2020 | 1951 | 2020 |
| Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design EO Saphire, PWHI Parren, R Pantophlet, MB Zwick, GM Morris, PM Rudd, ... science 293 (5532), 1155-1159, 2001 | 1153 | 2001 |
| Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41 MB Zwick, AF Labrijn, M Wang, C Spenlehauer, EO Saphire, JM Binley, ... Journal of virology 75 (22), 10892-10905, 2001 | 1045 | 2001 |
| Structure of the Ebola virus glycoprotein bound to an antibody from a human survivor JE Lee, ML Fusco, AJ Hessell, WB Oswald, DR Burton, EO Saphire Nature 454 (7201), 177-182, 2008 | 883 | 2008 |
| The broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2G12 recognizes a cluster of α1→ 2 mannose residues on the outer face of gp120 CN Scanlan, R Pantophlet, MR Wormald, E Ollmann Saphire, R Stanfield, ... Journal of virology 76 (14), 7306-7321, 2002 | 868 | 2002 |
| Complement is activated by IgG hexamers assembled at the cell surface CA Diebolder, FJ Beurskens, RN De Jong, RI Koning, K Strumane, ... Science 343 (6176), 1260-1263, 2014 | 853 | 2014 |
| Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling WB Cárdenas, YM Loo, M Gale Jr, AL Hartman, CR Kimberlin, ... Journal of virology 80 (11), 5168-5178, 2006 | 573 | 2006 |
| gp120: Biologic aspects of structural features P Poignard, EO Saphire, PWHI Parren, DR Burton Annual review of immunology 19 (1), 253-274, 2001 | 378 | 2001 |
| Ebolavirus Glycoprotein Structure and Mechanism of Entry JE Lee, EO Saphire Future virology 4 (6), 621-635, 2009 | 375 | 2009 |
| Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3′ to 5′ exonuclease activity essential for immune suppression KM Hastie, CR Kimberlin, MA Zandonatti, IJ MacRae, EO Saphire Proceedings of the National Academy of Sciences 108 (6), 2396-2401, 2011 | 320 | 2011 |
| Fine mapping of the interaction of neutralizing and nonneutralizing monoclonal antibodies with the CD4 binding site of human immunodeficiency virus type 1 gp120 R Pantophlet, E Ollmann Saphire, P Poignard, PWHI Parren, IA Wilson, ... Journal of virology 77 (1), 642-658, 2003 | 315 | 2003 |
| Defining variant-resistant epitopes targeted by SARS-CoV-2 antibodies: A global consortium study KM Hastie, H Li, D Bedinger, SL Schendel, SM Dennison, K Li, ... Science 374 (6566), 472-478, 2021 | 308 | 2021 |
| Contrasting IgG structures reveal extreme asymmetry and flexibility EO Saphire, RL Stanfield, MDM Crispin, PWHI Parren, PM Rudd, ... Journal of molecular biology 319 (1), 9-18, 2002 | 305 | 2002 |
| Structural rearrangement of ebola virus VP40 begets multiple functions in the virus life cycle ZA Bornholdt, T Noda, DM Abelson, P Halfmann, MR Wood, Y Kawaoka, ... Cell 154 (4), 763-774, 2013 | 275 | 2013 |
| Sheffield COVID-19 Genomics Group B Korber, WM Fischer, S Gnanakaran, H Yoon, J Theiler, W Abfalterer, ... Tracking changes in SARS-CoV-2 spike: evidence that D614G increases …, 2020 | 272 | 2020 |
| Lassa fever in post-conflict Sierra Leone JG Shaffer, DS Grant, JS Schieffelin, ML Boisen, A Goba, JN Hartnett, ... PLoS neglected tropical diseases 8 (3), e2748, 2014 | 268 | 2014 |
| Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak ZA Bornholdt, HL Turner, CD Murin, W Li, D Sok, CA Souders, AE Piper, ... Science 351 (6277), 1078-1083, 2016 | 243 | 2016 |
| A role for Fc function in therapeutic monoclonal antibody-mediated protection against Ebola virus BM Gunn, WH Yu, MM Karim, JM Brannan, AS Herbert, AZ Wec, ... Cell host & microbe 24 (2), 221-233. e5, 2018 | 237 | 2018 |
ParrenLeiden University Medical CenterVerified email at lumc.nl
