RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins N Mailand, S Bekker-Jensen, H Faustrup, F Melander, J Bartek, C Lukas, ... Cell 131 (5), 887-900, 2007 | 1364 | 2007 |
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins C Doil, N Mailand, S Bekker-Jensen, P Menard, DH Larsen, R Pepperkok, ... Cell 136 (3), 435-446, 2009 | 1087 | 2009 |
ATR prohibits replication catastrophe by preventing global exhaustion of RPA LI Toledo, M Altmeyer, MB Rask, C Lukas, DH Larsen, LK Povlsen, ... Cell 155 (5), 1088-1103, 2013 | 917 | 2013 |
Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM-and KAP-1 dependent pathway Y Ziv, D Bielopolski, Y Galanty, C Lukas, Y Taya, DC Schultz, J Lukas, ... Nature cell biology 8 (8), 870-876, 2006 | 878 | 2006 |
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks S Bekker-Jensen, C Lukas, R Kitagawa, F Melander, MB Kastan, J Bartek, ... The Journal of cell biology 173 (2), 195-206, 2006 | 758 | 2006 |
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress C Lukas, V Savic, S Bekker-Jensen, C Doil, B Neumann, ... Nature cell biology 13 (3), 243-253, 2011 | 737 | 2011 |
Mdc1 couples DNA double‐strand break recognition by Nbs1 with its H2AX‐dependent chromatin retention C Lukas, F Melander, M Stucki, J Falck, S Bekker‐Jensen, M Goldberg, ... The EMBO journal 23 (13), 2674-2683, 2004 | 518 | 2004 |
Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage T Thorslund, A Ripplinger, S Hoffmann, T Wild, M Uckelmann, ... Nature 527 (7578), 389-393, 2015 | 432 | 2015 |
Regulation of PCNA–protein interactions for genome stability N Mailand, I Gibbs-Seymour, S Bekker-Jensen Nature reviews Molecular cell biology 14 (5), 269-282, 2013 | 430 | 2013 |
The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity RB Damgaard, U Nachbur, M Yabal, WWL Wong, BK Fiil, M Kastirr, ... Molecular cell 46 (6), 746-758, 2012 | 412 | 2012 |
Assembly and function of DNA double-strand break repair foci in mammalian cells S Bekker-Jensen, N Mailand DNA repair 9 (12), 1219-1228, 2010 | 402 | 2010 |
Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers P Schwertman, S Bekker-Jensen, N Mailand Nature reviews Molecular cell biology 17 (6), 379-394, 2016 | 396 | 2016 |
HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes S Bekker-Jensen, JR Danielsen, K Fugger, I Gromova, A Nerstedt, ... Nature cell biology 12 (1), 80-86, 2010 | 372 | 2010 |
Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level JMR Danielsen, KB Sylvestersen, S Bekker-Jensen, D Szklarczyk, ... Molecular & Cellular Proteomics 10 (3), 2011 | 367 | 2011 |
TRIP12 and UBR5 suppress spreading of chromatin ubiquitylation at damaged chromosomes T Gudjonsson, M Altmeyer, V Savic, L Toledo, C Dinant, M Grøfte, ... Cell 150 (4), 697-709, 2012 | 366 | 2012 |
Dynamic assembly and sustained retention of 53BP1 at the sites of DNA damage are controlled by Mdc1/NFBD1 S Bekker-Jensen, C Lukas, F Melander, J Bartek, J Lukas The Journal of cell biology 170 (2), 201-211, 2005 | 363 | 2005 |
Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass LK Povlsen, P Beli, SA Wagner, SL Poulsen, KB Sylvestersen, ... Nature cell biology 14 (10), 1089-1098, 2012 | 303 | 2012 |
Destruction of Claspin by SCFβTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress N Mailand, S Bekker-Jensen, J Bartek, J Lukas Molecular cell 23 (3), 307-318, 2006 | 302 | 2006 |
Activation of the ATR kinase by the RPA-binding protein ETAA1 P Haahr, S Hoffmann, MAX Tollenaere, T Ho, LI Toledo, M Mann, ... Nature cell biology 18 (11), 1196-1207, 2016 | 275 | 2016 |
OTULIN restricts Met1-linked ubiquitination to control innate immune signaling BK Fiil, RB Damgaard, SA Wagner, K Keusekotten, M Fritsch, ... Molecular cell 50 (6), 818-830, 2013 | 273 | 2013 |