|Drug repurposing for gastrointestinal stromal tumor|
ZY Pessetto, SJ Weir, G Sethi, MA Broward, AK Godwin
Molecular cancer therapeutics 12 (7), 1299-1309, 2013
|High dose parenteral ascorbate inhibited pancreatic cancer growth and metastasis: mechanisms and a phase I/IIa study|
K Polireddy, R Dong, G Reed, J Yu, P Chen, S Williamson, PC Violet, ...
Scientific reports 7 (1), 1-15, 2017
|Inhibition of BRCT (BRCA1)-phosphoprotein interaction enhances the cytotoxic effect of olaparib in breast cancer cells: a proof of concept study for synthetic lethal …|
ZY Pessetto, Y Yan, T Bessho, A Natarajan
Breast cancer research and treatment 134 (2), 511-517, 2012
|Drug repurposing identifies a synergistic combination therapy with imatinib mesylate for gastrointestinal stromal tumor|
ZY Pessetto, Y Ma, JJ Hirst, M Von Mehren, SJ Weir, AK Godwin
Molecular cancer therapeutics 13 (10), 2276-2287, 2014
|Computational and experimental studies of the interaction between phospho-peptides and the C-terminal domain of BRCA1|
VM Anisimov, A Ziemys, S Kizhake, Z Yuan, A Natarajan, CN Cavasotto
Journal of computer-aided molecular design 25 (11), 1071-1084, 2011
|In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma|
ZY Pessetto, B Chen, H Alturkmani, S Hyter, CA Flynn, M Baltezor, Y Ma, ...
Oncotarget 8 (3), 4079, 2017
|Exploiting the P-1 pocket of BRCT domains toward a structure guided inhibitor design|
Z Yuan, EA Kumar, SJ Campbell, NY Palermo, S Kizhake, JNM Glover, ...
ACS medicinal chemistry letters 2 (10), 764-767, 2011
|Epimorphin-induced MET sensitizes ovarian cancer cells to platinum|
KH Yew, J Crow, J Hirst, Z Pressetto, AK Godwin
PloS one 8 (9), e72637, 2013
|Role of miR-139 as a surrogate marker for tumor aggression in breast cancer|
H Dai, D Gallagher, S Schmitt, ZY Pessetto, F Fan, AK Godwin, O Tawfik
Human pathology 61, 68-77, 2017
|Structure–activity relationship studies to probe the phosphoprotein binding site on the carboxy terminal domains of the breast cancer susceptibility gene 1|
Z Yuan, EA Kumar, S Kizhake, A Natarajan
Journal of medicinal chemistry 54 (12), 4264-4268, 2011
|Licofelone enhances the efficacy of paclitaxel in ovarian cancer by reversing drug resistance and tumor stem-like properties|
J Hirst, HB Pathak, S Hyter, ZY Pessetto, T Ly, S Graw, DC Koestler, ...
Cancer research 78 (15), 4370-4385, 2018
|Clinical and biomarker results from phase I/II study of PI3K inhibitor BYL 719 (alpelisib) plus nab-paclitaxel in HER2-negative metastatic breast cancer.|
P Sharma, VG Abramson, A O'Dea, HB Pathak, ZY Pessetto, YY Wang, ...
Journal of Clinical Oncology 36 (15_suppl), 1018-1018, 2018
|Structural characterization of BRCT–tetrapeptide binding interactions|
PRB Joseph, Z Yuan, EA Kumar, GL Lokesh, S Kizhake, K Rajarathnam, ...
Biochemical and biophysical research communications 393 (2), 207-210, 2010
|Peptide truncation leads to a twist and an unusual increase in affinity for casitas B-lineage lymphoma tyrosine kinase binding domain|
EA Kumar, Z Yuan, NY Palermo, L Dong, G Ahmad, GL Lokesh, C Kolar, ...
Journal of medicinal chemistry 55 (7), 3583-3587, 2012
|Design, Optimization, and Multisite Evaluation of a Targeted Next-Generation Sequencing Assay System for Chimeric RNAs from Gene Fusions and Exon-Skipping Events in Non–Small …|
RA Blidner, BC Haynes, S Hyter, S Schmitt, ZY Pessetto, AK Godwin, ...
The Journal of Molecular Diagnostics 21 (2), 352-365, 2019
|Development of a fluorescence polarization based high-throughput assay to identify Casitas B-lineage lymphoma RING domain regulators|
X Xie, L Sun, ZY Pessetto, Y Zhao, Z Zang, L Zhong, M Wu, Q Su, X Gao, ...
PloS one 8 (10), e78042, 2013
|Beyond standard therapy: drugs under investigation for the treatment of gastrointestinal stromal tumor|
HJ Alturkmani, ZY Pessetto, AK Godwin
Expert opinion on investigational drugs 24 (8), 1045-1058, 2015
|Casitas B-Lineage Lymphoma RING Domain Inhibitors Protect Mice against High-Fat Diet-Induced Obesity and Insulin Resistance|
M Wu, L Sun, ZY Pessetto, Z Zang, X Xie, L Zhong, Q Su, W Zan, X Gao, ...
PLoS One 10 (8), e0135916, 2015
|Niraparib in metastatic pancreatic cancer after previous chemotherapy (NIRA-PANC): A phase 2 trial.|
A Kasi, P Chalise, SK Williamson, JC Baranda, W Sun, RMT Al-Rajabi, ...
Journal of Clinical Oncology 37 (15_suppl), TPS4168-TPS4168, 2019
|Developing a genetic signature to predict drug response in ovarian cancer|
S Hyter, J Hirst, H Pathak, ZY Pessetto, DC Koestler, R Raghavan, D Pei, ...
Oncotarget 9 (19), 14828, 2018