Ziyan Pessetto
Ziyan Pessetto
University of Kansas Medical Center
Dirección de correo verificada de kumc.edu
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Drug repurposing for gastrointestinal stromal tumor
ZY Pessetto, SJ Weir, G Sethi, MA Broward, AK Godwin
Molecular cancer therapeutics 12 (7), 1299-1309, 2013
702013
High dose parenteral ascorbate inhibited pancreatic cancer growth and metastasis: mechanisms and a phase I/IIa study
K Polireddy, R Dong, G Reed, J Yu, P Chen, S Williamson, PC Violet, ...
Scientific reports 7 (1), 1-15, 2017
472017
Inhibition of BRCT (BRCA1)-phosphoprotein interaction enhances the cytotoxic effect of olaparib in breast cancer cells: a proof of concept study for synthetic lethal …
ZY Pessetto, Y Yan, T Bessho, A Natarajan
Breast cancer research and treatment 134 (2), 511-517, 2012
372012
Drug repurposing identifies a synergistic combination therapy with imatinib mesylate for gastrointestinal stromal tumor
ZY Pessetto, Y Ma, JJ Hirst, M Von Mehren, SJ Weir, AK Godwin
Molecular cancer therapeutics 13 (10), 2276-2287, 2014
342014
Computational and experimental studies of the interaction between phospho-peptides and the C-terminal domain of BRCA1
VM Anisimov, A Ziemys, S Kizhake, Z Yuan, A Natarajan, CN Cavasotto
Journal of computer-aided molecular design 25 (11), 1071-1084, 2011
272011
In silico and in vitro drug screening identifies new therapeutic approaches for Ewing sarcoma
ZY Pessetto, B Chen, H Alturkmani, S Hyter, CA Flynn, M Baltezor, Y Ma, ...
Oncotarget 8 (3), 4079, 2017
222017
Exploiting the P-1 pocket of BRCT domains toward a structure guided inhibitor design
Z Yuan, EA Kumar, SJ Campbell, NY Palermo, S Kizhake, JNM Glover, ...
ACS medicinal chemistry letters 2 (10), 764-767, 2011
222011
Epimorphin-induced MET sensitizes ovarian cancer cells to platinum
KH Yew, J Crow, J Hirst, Z Pressetto, AK Godwin
PloS one 8 (9), e72637, 2013
212013
Role of miR-139 as a surrogate marker for tumor aggression in breast cancer
H Dai, D Gallagher, S Schmitt, ZY Pessetto, F Fan, AK Godwin, O Tawfik
Human pathology 61, 68-77, 2017
182017
Structure–activity relationship studies to probe the phosphoprotein binding site on the carboxy terminal domains of the breast cancer susceptibility gene 1
Z Yuan, EA Kumar, S Kizhake, A Natarajan
Journal of medicinal chemistry 54 (12), 4264-4268, 2011
172011
Licofelone enhances the efficacy of paclitaxel in ovarian cancer by reversing drug resistance and tumor stem-like properties
J Hirst, HB Pathak, S Hyter, ZY Pessetto, T Ly, S Graw, DC Koestler, ...
Cancer research 78 (15), 4370-4385, 2018
152018
Clinical and biomarker results from phase I/II study of PI3K inhibitor BYL 719 (alpelisib) plus nab-paclitaxel in HER2-negative metastatic breast cancer.
P Sharma, VG Abramson, A O'Dea, HB Pathak, ZY Pessetto, YY Wang, ...
Journal of Clinical Oncology 36 (15_suppl), 1018-1018, 2018
132018
Structural characterization of BRCT–tetrapeptide binding interactions
PRB Joseph, Z Yuan, EA Kumar, GL Lokesh, S Kizhake, K Rajarathnam, ...
Biochemical and biophysical research communications 393 (2), 207-210, 2010
122010
Peptide truncation leads to a twist and an unusual increase in affinity for casitas B-lineage lymphoma tyrosine kinase binding domain
EA Kumar, Z Yuan, NY Palermo, L Dong, G Ahmad, GL Lokesh, C Kolar, ...
Journal of medicinal chemistry 55 (7), 3583-3587, 2012
112012
Design, Optimization, and Multisite Evaluation of a Targeted Next-Generation Sequencing Assay System for Chimeric RNAs from Gene Fusions and Exon-Skipping Events in Non–Small …
RA Blidner, BC Haynes, S Hyter, S Schmitt, ZY Pessetto, AK Godwin, ...
The Journal of Molecular Diagnostics 21 (2), 352-365, 2019
82019
Development of a fluorescence polarization based high-throughput assay to identify Casitas B-lineage lymphoma RING domain regulators
X Xie, L Sun, ZY Pessetto, Y Zhao, Z Zang, L Zhong, M Wu, Q Su, X Gao, ...
PloS one 8 (10), e78042, 2013
52013
Beyond standard therapy: drugs under investigation for the treatment of gastrointestinal stromal tumor
HJ Alturkmani, ZY Pessetto, AK Godwin
Expert opinion on investigational drugs 24 (8), 1045-1058, 2015
42015
Casitas B-Lineage Lymphoma RING Domain Inhibitors Protect Mice against High-Fat Diet-Induced Obesity and Insulin Resistance
M Wu, L Sun, ZY Pessetto, Z Zang, X Xie, L Zhong, Q Su, W Zan, X Gao, ...
PLoS One 10 (8), e0135916, 2015
22015
Niraparib in metastatic pancreatic cancer after previous chemotherapy (NIRA-PANC): A phase 2 trial.
A Kasi, P Chalise, SK Williamson, JC Baranda, W Sun, RMT Al-Rajabi, ...
Journal of Clinical Oncology 37 (15_suppl), TPS4168-TPS4168, 2019
12019
Developing a genetic signature to predict drug response in ovarian cancer
S Hyter, J Hirst, H Pathak, ZY Pessetto, DC Koestler, R Raghavan, D Pei, ...
Oncotarget 9 (19), 14828, 2018
12018
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