Eric E. Kelley
Eric E. Kelley
Professor and Vice Chair for Research, Physiology and Pharmacology, West Virginia University
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Nitric oxide scavenging by red blood cell microparticles and cell-free hemoglobin as a mechanism for the red cell storage lesion
C Donadee, NJH Raat, T Kanias, J Tejero, JS Lee, EE Kelley, X Zhao, ...
Circulation 124 (4), 465-476, 2011
Hydrogen peroxide is the major oxidant product of xanthine oxidase
EE Kelley, NKH Khoo, NJ Hundley, UZ Malik, BA Freeman, MM Tarpey
Free Radical Biology and Medicine 48 (4), 493-498, 2010
Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent
AL King, DJ Polhemus, S Bhushan, H Otsuka, K Kondo, CK Nicholson, ...
Proceedings of the National Academy of Sciences 111 (8), 3182-3187, 2014
An aged immune system drives senescence and ageing of solid organs
MJ Yousefzadeh, RR Flores, YI Zhu, ZC Schmiechen, RW Brooks, ...
Nature 594 (7861), 100-105, 2021
Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling
I Al Ghouleh, NKH Khoo, UG Knaus, KK Griendling, RM Touyz, ...
Free Radical Biology and Medicine 51 (7), 1271-1288, 2011
Inhaled NO accelerates restoration of liver function in adults following orthotopic liver transplantation
JD Lang, X Teng, P Chumley, JH Crawford, TS Isbell, BK Chacko, Y Liu, ...
The Journal of clinical investigation 117 (9), 2583-2591, 2007
Xanthine oxidoreductase-catalyzed reactive species generation: a process in critical need of reevaluation
N Cantu-Medellin, EE Kelley
Redox biology 1 (1), 353-358, 2013
Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species
ER Hahm, MB Moura, EE Kelley, B Van Houten, S Shiva, SV Singh
PloS one 6 (8), e23354, 2011
Phenethyl isothiocyanate inhibits oxidative phosphorylation to trigger reactive oxygen species-mediated death of human prostate cancer cells
D Xiao, AA Powolny, MB Moura, EE Kelley, A Bommareddy, SH Kim, ...
Journal of Biological Chemistry 285 (34), 26558-26569, 2010
Xanthine oxidoreductase-catalyzed reduction of nitrite to nitric oxide: insights regarding where, when and how
N Cantu-Medellin, EE Kelley
Nitric Oxide 34, 19-26, 2013
Comparing β-carotene, vitamin E and nitric oxide as membrane antioxidants
FQ Schafer, HP Wang, EE Kelley, KL Cueno, SMMGR Buettner
Walter de Gruyter 383 (3-4), 671-681, 2002
Nox2 B-loop peptide, Nox2ds, specifically inhibits the NADPH oxidase Nox2
G Csányi, E Cifuentes-Pagano, I Al Ghouleh, DJ Ranayhossaini, L Egaña, ...
Free Radical Biology and Medicine 51 (6), 1116-1125, 2011
Febuxostat inhibition of endothelial-bound XO: implications for targeting vascular ROS production
UZ Malik, NJ Hundley, G Romero, R Radi, BA Freeman, MM Tarpey, ...
Free Radical Biology and Medicine 51 (1), 179-184, 2011
Uric acid and hypertension: an update with recommendations
LG Sanchez-Lozada, B Rodriguez-Iturbe, EE Kelley, T Nakagawa, ...
American journal of hypertension 33 (7), 583-594, 2020
Thrombospondin-1 regulates blood flow via CD47 receptor–mediated activation of NADPH oxidase 1
G Csányi, M Yao, AI Rodríguez, IA Ghouleh, M Sharifi-Sanjani, ...
Arteriosclerosis, thrombosis, and vascular biology 32 (12), 2966-2973, 2012
Nitrite-generated NO circumvents dysregulated arginine/NOS signaling to protect against intimal hyperplasia in Sprague-Dawley rats
MJ Alef, R Vallabhaneni, E Carchman, SM Morris, S Shiva, Y Wang, ...
The Journal of clinical investigation 121 (4), 1646-1656, 2011
Xanthine oxidase–dependent regulation of hypoxia-inducible factor in cancer cells
CE Griguer, CR Oliva, EE Kelley, GI Giles, JR Lancaster Jr, GY Gillespie
Cancer research 66 (4), 2257-2263, 2006
Activation of the aryl hydrocarbon receptor sensitizes mice to nonalcoholic steatohepatitis by deactivating mitochondrial sirtuin deacetylase Sirt3
J He, B Hu, X Shi, ER Weidert, P Lu, M Xu, M Huang, EE Kelley, W Xie
Molecular and cellular biology 33 (10), 2047-2055, 2013
Nitro-oleic acid, a novel and irreversible inhibitor of xanthine oxidoreductase
EE Kelley, CI Batthyany, NJ Hundley, SR Woodcock, G Bonacci, ...
Journal of Biological Chemistry 283 (52), 36176-36184, 2008
Moderate hypoxia induces xanthine oxidoreductase activity in arterial endothelial cells
EE Kelley, T Hock, NKH Khoo, GR Richardson, KK Johnson, PC Powell, ...
Free Radical Biology and Medicine 40 (6), 952-959, 2006
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