Peter D Mace
Peter D Mace
Professor, University of Otago, New Zealand
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Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans
K Linke, PD Mace, CA Smith, DL Vaux, J Silke, CL Day
Cell death & differentiation 15 (5), 841-848, 2008
TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (TNF) to efficiently activate NF-κB and to prevent TNF-induced apoptosis
JE Vince, D Pantaki, R Feltham, PD Mace, SM Cordier, AC Schmukle, ...
Journal of Biological Chemistry 284 (51), 35906, 2009
Structures of the cIAP2 RING domain reveal conformational changes associated with ubiquitin-conjugating enzyme (E2) recruitment
PD Mace, K Linke, R Feltham, FR Schumacher, CA Smith, DL Vaux, ...
Journal of Biological Chemistry 283 (46), 31633-31640, 2008
The CARD plays a critical role in ASC foci formation and inflammasome signalling
M Proell, M Gerlic, PD Mace, JC Reed, SJ Riedl
Biochemical Journal 449 (3), 613-621, 2013
Smac mimetics activate the E3 ligase activity of cIAP1 protein by promoting RING domain dimerization
R Feltham, B Bettjeman, R Budhidarmo, PD Mace, S Shirley, SM Condon, ...
Journal of Biological Chemistry 286 (19), 17015-17028, 2011
Structure of a HOIP/E2~ ubiquitin complex reveals RBR E3 ligase mechanism and regulation
BC Lechtenberg, A Rajput, R Sanishvili, MK Dobaczewska, CF Ware, ...
Nature 529 (7587), 546-550, 2016
Assembling the building blocks: structure and function of inhibitor of apoptosis proteins
PD Mace, S Shirley, CL Day
Cell Death & Differentiation 17 (1), 46-53, 2010
Structural mechanisms in NLR inflammasome signaling
BC Lechtenberg, PD Mace, SJ Riedl
Current opinion in structural biology 29, 17-25, 2014
Molecular mechanism of CCAAT-enhancer binding protein recruitment by the TRIB1 pseudokinase
JM Murphy, Y Nakatani, SA Jamieson, W Dai, IS Lucet, PD Mace
Structure 23 (11), 2111-2121, 2015
Molecular cell death platforms and assemblies
PD Mace, SJ Riedl
Current opinion in cell biology 22 (6), 828-836, 2010
Live and let die: insights into pseudoenzyme mechanisms from structure
JM Murphy, PD Mace, PA Eyers
Current opinion in structural biology 47, 95-104, 2017
Activation and specificity of human caspase-10
K Wachmann, C Pop, BJ van Raam, M Drag, PD Mace, SJ Snipas, ...
Biochemistry 49 (38), 8307-8315, 2010
Asymmetric recruitment of cIAPs by TRAF2
PD Mace, C Smits, DL Vaux, J Silke, CL Day
Journal of molecular biology 400 (1), 8-15, 2010
Structure of ERK2 bound to PEA-15 reveals a mechanism for rapid release of activated MAPK
PD Mace, Y Wallez, MF Egger, MK Dobaczewska, H Robinson, ...
Nature communications 4 (1), 1681, 2013
Identification of highly selective covalent inhibitors by phage display
S Chen, S Lovell, S Lee, M Fellner, PD Mace, M Bogyo
Nature biotechnology 39 (4), 490-498, 2021
Expedient synthesis of highly potent antagonists of inhibitor of apoptosis proteins (IAPs) with unique selectivity for ML-IAP
M Vamos, K Welsh, D Finlay, PS Lee, PD Mace, SJ Snipas, ML Gonzalez, ...
ACS chemical biology 8 (4), 725-732, 2013
High resolution structures of the bone morphogenetic protein type II receptor in two crystal forms: implications for ligand binding
PD Mace, JF Cutfield, SM Cutfield
Biochemical and biophysical research communications 351 (4), 831-838, 2006
When worlds collide—mechanisms at the interface between phosphorylation and ubiquitination
P Filipčík, JR Curry, PD Mace
Journal of molecular biology 429 (8), 1097-1113, 2017
Substrate binding allosterically relieves autoinhibition of the pseudokinase TRIB1
SA Jamieson, Z Ruan, AE Burgess, JR Curry, HD McMillan, JL Brewster, ...
Science signaling 11 (549), eaau0597, 2018
There’s more to death than life: Noncatalytic functions in kinase and pseudokinase signaling
PD Mace, JM Murphy
Journal of Biological Chemistry 296, 2021
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Artículos 1–20