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Peter H Backx
Peter H Backx
department of biology York university
Verified email at yorku.ca
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Cited by
Cited by
Year
Angiotensin-converting enzyme 2 is an essential regulator of heart function
MA Crackower, R Sarao, GY Oudit, C Yagil, I Kozieradzki, SE Scanga, ...
Nature 417 (6891), 822-828, 2002
23502002
VEGF inhibition and renal thrombotic microangiopathy
V Eremina, JA Jefferson, J Kowalewska, H Hochster, M Haas, J Weisstuch, ...
New England Journal of Medicine 358 (11), 1129-1136, 2008
17672008
Biowire: a platform for maturation of human pluripotent stem cell–derived cardiomyocytes
SS Nunes, JW Miklas, J Liu, R Aschar-Sobbi, Y Xiao, B Zhang, J Jiang, ...
Nature methods 10 (8), 781-787, 2013
11032013
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways
MA Crackower, GY Oudit, I Kozieradzki, R Sarao, H Sun, T Sasaki, ...
Cell 110 (6), 737-749, 2002
8062002
The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease
GY Oudit, H Sun, BG Kerfant, MA Crackower, JM Penninger, PH Backx
Journal of molecular and cellular cardiology 37 (2), 449-471, 2004
6382004
L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy
GY Oudit, H Sun, MG Trivieri, SE Koch, F Dawood, C Ackerley, ...
Nature medicine 9 (9), 1187-1194, 2003
5712003
GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure
M Kim, MJ Platt, T Shibasaki, SE Quaggin, PH Backx, S Seino, ...
Nature medicine 19 (5), 567-575, 2013
5522013
A platform for generation of chamber-specific cardiac tissues and disease modeling
Y Zhao, N Rafatian, NT Feric, BJ Cox, R Aschar-Sobbi, EY Wang, ...
Cell 176 (4), 913-927. e18, 2019
5472019
Human pluripotent stem cell-derived atrial and ventricular cardiomyocytes develop from distinct mesoderm populations
JH Lee, SI Protze, Z Laksman, PH Backx, GM Keller
Cell stem cell 21 (2), 179-194. e4, 2017
4332017
Circadian rhythm disorganization produces profound cardiovascular and renal disease in hamsters
TA Martino, GY Oudit, AM Herzenberg, N Tata, MM Koletar, GM Kabir, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2008
3812008
Sinoatrial node cardiomyocytes derived from human pluripotent cells function as a biological pacemaker
SI Protze, J Liu, U Nussinovitch, L Ohana, PH Backx, L Gepstein, ...
Nature biotechnology 35 (1), 56-68, 2017
3752017
Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis
F Lovren, Y Pan, A Quan, H Teoh, G Wang, PC Shukla, KS Levitt, ...
American Journal of Physiology-Heart and Circulatory Physiology 295 (4 …, 2008
3742008
The role of ACE2 in cardiovascular physiology
GY Oudit, MA Crackower, PH Backx, JM Penninger
Trends in cardiovascular medicine 13 (3), 93-101, 2003
3732003
A circular RNA binds to and activates AKT phosphorylation and nuclear localization reducing apoptosis and enhancing cardiac repair
Y Zeng, WW Du, Y Wu, Z Yang, FM Awan, X Li, W Yang, C Zhang, Q Yang, ...
Theranostics 7 (16), 3842, 2017
3692017
Molecular localization of an ion-binding site within the pore of mammalian sodium channels
PH Backx, DT Yue, JH Lawrence, E Marban, GF Tomaselli
Science 257 (5067), 248-251, 1992
3441992
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury
DW Wong, GY Oudit, H Reich, Z Kassiri, J Zhou, QC Liu, PH Backx, ...
The American journal of pathology 171 (2), 438-451, 2007
3422007
Relationship Between Intracellular Calcium and Contractile Force in Stunned Myocardium: Direct Evidence for Decreased Myofilament Ca2+ Responsiveness and …
WD Gao, D Atar, PH Backx, E Marban
Circulation research 76 (6), 1036-1048, 1995
3151995
Regulation of cardiac excitation–contraction coupling by action potential repolarization: role of the transient outward potassium current (Ito)
R Sah, RJ Ramirez, GY Oudit, D Gidrewicz, MG Trivieri, C Zobel, ...
The Journal of physiology 546 (1), 5-18, 2003
3102003
Excitation-transcription coupling mediated by zinc influx through voltage-dependent calcium channels (∗)
D Atar, PH Backx, MM Appel, WD Gao, E Marban
Journal of Biological Chemistry 270 (6), 2473-2477, 1995
3021995
The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient
DL Costantini, EP Arruda, P Agarwal, KH Kim, Y Zhu, W Zhu, M Lebel, ...
Cell 123 (2), 347-358, 2005
2982005
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