Peter H Backx
Peter H Backx
department of biology York university
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Angiotensin-converting enzyme 2 is an essential regulator of heart function
MA Crackower, R Sarao, GY Oudit, C Yagil, I Kozieradzki, SE Scanga, ...
Nature 417 (6891), 822-828, 2002
VEGF inhibition and renal thrombotic microangiopathy
V Eremina, JA Jefferson, J Kowalewska, H Hochster, M Haas, J Weisstuch, ...
New England Journal of Medicine 358 (11), 1129-1136, 2008
Biowire: a platform for maturation of human pluripotent stem cell–derived cardiomyocytes
SS Nunes, JW Miklas, J Liu, R Aschar-Sobbi, Y Xiao, B Zhang, J Jiang, ...
Nature methods 10 (8), 781-787, 2013
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways
MA Crackower, GY Oudit, I Kozieradzki, R Sarao, H Sun, T Sasaki, ...
Cell 110 (6), 737-749, 2002
The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease
GY Oudit, H Sun, BG Kerfant, MA Crackower, JM Penninger, PH Backx
Journal of molecular and cellular cardiology 37 (2), 449-471, 2004
L-type Ca2+ channels provide a major pathway for iron entry into cardiomyocytes in iron-overload cardiomyopathy
GY Oudit, H Sun, MG Trivieri, SE Koch, F Dawood, C Ackerley, ...
Nature medicine 9 (9), 1187-1194, 2003
GLP-1 receptor activation and Epac2 link atrial natriuretic peptide secretion to control of blood pressure
M Kim, MJ Platt, T Shibasaki, SE Quaggin, PH Backx, S Seino, ...
Nature medicine 19 (5), 567-575, 2013
A platform for generation of chamber-specific cardiac tissues and disease modeling
Y Zhao, N Rafatian, NT Feric, BJ Cox, R Aschar-Sobbi, EY Wang, ...
Cell 176 (4), 913-927. e18, 2019
Human pluripotent stem cell-derived atrial and ventricular cardiomyocytes develop from distinct mesoderm populations
JH Lee, SI Protze, Z Laksman, PH Backx, GM Keller
Cell stem cell 21 (2), 179-194. e4, 2017
The role of ACE2 in cardiovascular physiology
GY Oudit, MA Crackower, PH Backx, JM Penninger
Trends in cardiovascular medicine 13 (3), 93-101, 2003
Angiotensin converting enzyme-2 confers endothelial protection and attenuates atherosclerosis
F Lovren, Y Pan, A Quan, H Teoh, G Wang, PC Shukla, KS Levitt, ...
American Journal of Physiology-Heart and Circulatory Physiology 295 (4 …, 2008
Circadian rhythm disorganization produces profound cardiovascular and renal disease in hamsters
TA Martino, GY Oudit, AM Herzenberg, N Tata, MM Koletar, GM Kabir, ...
American Journal of Physiology-Regulatory, Integrative and Comparative …, 2008
Sinoatrial node cardiomyocytes derived from human pluripotent cells function as a biological pacemaker
SI Protze, J Liu, U Nussinovitch, L Ohana, PH Backx, L Gepstein, ...
Nature biotechnology 35 (1), 56-68, 2017
A circular RNA binds to and activates AKT phosphorylation and nuclear localization reducing apoptosis and enhancing cardiac repair
Y Zeng, WW Du, Y Wu, Z Yang, FM Awan, X Li, W Yang, C Zhang, Q Yang, ...
Theranostics 7 (16), 3842, 2017
Molecular localization of an ion-binding site within the pore of mammalian sodium channels
PH Backx, DT Yue, JH Lawrence, E Marban, GF Tomaselli
Science 257 (5067), 248-251, 1992
Loss of angiotensin-converting enzyme-2 (Ace2) accelerates diabetic kidney injury
DW Wong, GY Oudit, H Reich, Z Kassiri, J Zhou, QC Liu, PH Backx, ...
The American journal of pathology 171 (2), 438-451, 2007
Relationship Between Intracellular Calcium and Contractile Force in Stunned Myocardium: Direct Evidence for Decreased Myofilament Ca2+ Responsiveness and …
WD Gao, D Atar, PH Backx, E Marban
Circulation research 76 (6), 1036-1048, 1995
Regulation of cardiac excitation–contraction coupling by action potential repolarization: role of the transient outward potassium current (Ito)
R Sah, RJ Ramirez, GY Oudit, D Gidrewicz, MG Trivieri, C Zobel, ...
The Journal of physiology 546 (1), 5-18, 2003
The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient
DL Costantini, EP Arruda, P Agarwal, KH Kim, Y Zhu, W Zhu, M Lebel, ...
Cell 123 (2), 347-358, 2005
Excitation-transcription coupling mediated by zinc influx through voltage-dependent calcium channels (∗)
D Atar, PH Backx, MM Appel, WD Gao, E Marban
Journal of Biological Chemistry 270 (6), 2473-2477, 1995
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