Mark Hannink
Mark Hannink
Life Sciences Center and Biochemistry Department, University of Missouri
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Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
DD Zhang, M Hannink
Molecular and cellular biology, 2003
Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex
DD Zhang, SC Lo, JV Cross, DJ Templeton, M Hannink
Molecular and cellular biology 24 (24), 10941-10953, 2004
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
SB Cullinan, D Zhang, M Hannink, E Arvisais, RJ Kaufman, JA Diehl
Molecular and cellular biology 23 (20), 7198-7209, 2003
Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1–dependent cellular transformation
JR Alt, JL Cleveland, M Hannink, JA Diehl
Genes & development 14 (24), 3102-3114, 2000
Structure of the Keap1: Nrf2 interface provides mechanistic insight into Nrf2 signaling
SC Lo, X Li, MT Henzl, LJ Beamer, M Hannink
The EMBO journal 25 (15), 3605-3617, 2006
The v-rel oncogene encodes a κB enhancer binding protein that inhibits NF-κB function
DW Ballard, WH Walker, S Doerre, P Sista, JA Molitor, EP Dixon, ...
Cell 63 (4), 803-814, 1990
Ubiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathway
DD Zhang, SC Lo, Z Sun, GM Habib, MW Lieberman, M Hannink
Journal of Biological Chemistry 280 (34), 30091-30099, 2005
PGAM5 tethers a ternary complex containing Keap1 and Nrf2 to mitochondria
SC Lo, M Hannink
Experimental cell research 314 (8), 1789-1803, 2008
Docosahexaenoic acid (DHA): An essential nutrient and a nutraceutical for brain health and diseases
GY Sun, A Simonyi, KL Fritsche, DY Chuang, M Hannink, Z Gu, ...
Prostaglandins, Leukotrienes and Essential Fatty Acids 136, 3-13, 2018
Crystal structure of the Kelch domain of human Keap1
X Li, D Zhang, M Hannink, LJ Beamer
Journal of Biological Chemistry 279 (52), 54750-54758, 2004
PGAM5, a Bcl-XL-interacting protein, is a novel substrate for the redox-regulated Keap1-dependent ubiquitin ligase complex
SC Lo, M Hannink
Journal of biological chemistry 281 (49), 37893-37903, 2006
Embryotoxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD): Theembryonic vasculature is a physiological target for TCDD-induced DNA damage and apoptotic cell death in …
SM Cantrell, LH Lutz, DE Tillitt, M Hannink
Toxicology and applied pharmacology 141 (1), 23-34, 1996
Nuclear Localization of IκBα Is Mediated by the Second Ankyrin Repeat: the IκBα Ankyrin Repeats Define a Novel Class of cis-Acting Nuclear Import Sequences
S Sachdev, A Hoffmann, M Hannink
Molecular and cellular biology 18 (5), 2524-2534, 1998
Cul3-mediated Nrf2 ubiquitination and antioxidant response element (ARE) activation are dependent on the partial molar volume at position 151 of Keap1
AL Eggler, E Small, M Hannink, AD Mesecar
Biochemical journal 422 (1), 171-180, 2009
Correlation of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced apoptotic cell death in the embryonic vasculature with embryotoxicity
SM Cantrell, J Joy-Schlezinger, JJ Stegeman, DE Tillitt, M Hannink
Toxicology and applied pharmacology 148 (1), 24-34, 1998
Quercetin attenuates inflammatory responses in BV-2 microglial cells: role of MAPKs on the Nrf2 pathway and induction of heme oxygenase-1
GY Sun, Z Chen, KJ Jasmer, DY Chuang, Z Gu, M Hannink, A Simonyi
PloS one 10 (10), e0141509, 2015
Structure and function of platelet-derived growth factor (PDGF) and related proteins
M Hannink, DJ Donoghue
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer 989 (1), 1-10, 1989
Identification of oxygen-sensitive transcriptional programs in human embryonic stem cells
SD Westfall, S Sachdev, P Das, LB Hearne, M Hannink, RM Roberts, ...
Stem cells and development 17 (5), 869-882, 2008
Modulation of Phototropic Responsiveness in Arabidopsis through Ubiquitination of Phototropin 1 by the CUL3-Ring E3 Ubiquitin Ligase CRL3NPH3
D Roberts, UV Pedmale, J Morrow, S Sachdev, E Lechner, X Tang, ...
The Plant Cell 23 (10), 3627-3640, 2011
Effects of interventions on oxidative stress and inflammation of cardiovascular diseases
S Lee, Y Park, MY Zuidema, M Hannink, C Zhang
World Journal of Cardiology 3 (1), 18, 2011
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Artículos 1–20