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Christopher Y. Ko
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Rb and p130 control cell cycle gene silencing to maintain the postmitotic phenotype in cardiac myocytes
P Sdek, P Zhao, Y Wang, C Huang, CY Ko, PC Butler, JN Weiss, ...
Journal of cell Biology 194 (3), 407-423, 2011
1922011
Calcium-voltage coupling in the genesis of early and delayed afterdepolarizations in cardiac myocytes
Z Song, CY Ko, M Nivala, JN Weiss, Z Qu
Biophysical journal 108 (8), 1908-1921, 2015
1132015
Molecular basis of hypokalemia-induced ventricular fibrillation
A Pezhouman, N Singh, Z Song, M Nivala, A Eskandari, H Cao, A Bapat, ...
Circulation 132 (16), 1528-1537, 2015
1052015
Criticality in intracellular calcium signaling in cardiac myocytes
M Nivala, CY Ko, M Nivala, JN Weiss, Z Qu
Biophysical journal 102 (11), 2433-2442, 2012
952012
THY-1 receptor expression differentiates cardiosphere-derived cells with divergent cardiogenic differentiation potential
N Gago-Lopez, O Awaji, Y Zhang, C Ko, A Nsair, D Liem, ...
Stem cell reports 2 (5), 576-591, 2014
602014
Myogenic Akt signaling upregulates the utrophin–glycoprotein complex and promotes sarcolemma stability in muscular dystrophy
AK Peter, CY Ko, MH Kim, N Hsu, N Ouchi, S Rhie, Y Izumiya, L Zeng, ...
Human molecular genetics 18 (2), 318-327, 2009
582009
CaMKII serine 280 O-GlcNAcylation links diabetic hyperglycemia to proarrhythmia
B Hegyi, A Fasoli, CY Ko, BW Van, CC Alim, EY Shen, MM Ciccozzi, ...
Circulation research 129 (1), 98-113, 2021
482021
Cardiomyocyte Na+ and Ca2+ mishandling drives vicious cycle involving CaMKII, ROS, and ryanodine receptors
B Hegyi, RP Pölönen, KT Hellgren, CY Ko, KS Ginsburg, J Bossuyt, ...
Basic research in cardiology 116, 1-16, 2021
432021
The emergence of subcellular pacemaker sites for calcium waves and oscillations
M Nivala, CY Ko, M Nivala, JN Weiss, Z Qu
The Journal of physiology 591 (21), 5305-5320, 2013
362013
Two-hit mechanism of cardiac arrhythmias in diabetic hyperglycaemia: reduced repolarization reserve, neurohormonal stimulation, and heart failure exacerbate susceptibility
B Hegyi, CY Ko, J Bossuyt, DM Bers
Cardiovascular research 117 (14), 2781-2793, 2021
272021
A dynamical threshold for cardiac delayed afterdepolarization-mediated triggered activity
MB Liu, CY Ko, Z Song, A Garfinkel, JN Weiss, Z Qu
Biophysical journal 111 (11), 2523-2533, 2016
232016
Multiscale determinants of delayed afterdepolarization amplitude in cardiac tissue
CY Ko, MB Liu, Z Song, Z Qu, JN Weiss
Biophysical Journal 112 (9), 1949-1961, 2017
192017
Acute reversal of phospholamban inhibition facilitates the rhythmic whole-cell propagating calcium waves in isolated ventricular myocytes
YH Chan, WC Tsai, Z Song, CY Ko, Z Qu, JN Weiss, SF Lin, PS Chen, ...
Journal of Molecular and Cellular Cardiology 80, 126-135, 2015
192015
Increased susceptibility of spontaneously hypertensive rats to ventricular tachyarrhythmias in early hypertension
TP Nguyen, AA Sovari, A Pezhouman, S Iyer, H Cao, CY Ko, A Bapat, ...
The Journal of physiology 594 (6), 1689-1707, 2016
172016
Diabetes and excess aldosterone promote heart failure with preserved ejection fraction
B Hegyi, J Mira Hernandez, CY Ko, J Hong, EY Shen, ER Spencer, ...
Journal of the American Heart Association 11 (23), e027164, 2022
102022
Synergistic FRET assays for drug discovery targeting RyR2 channels
RT Rebbeck, KS Ginsburg, CY Ko, A Fasoli, K Rusch, GF Cai, X Dong, ...
Journal of molecular and cellular cardiology 168, 13-23, 2022
82022
Nitrosylation of cardiac CaMKII at Cys290 mediates mechanical afterload‐induced increases in Ca2+ transient and Ca2+ sparks
CC Alim, CY Ko, J Mira Hernandez, EY Shen, S Baidar, Y Chen‐Izu, ...
The Journal of Physiology 600 (22), 4865-4879, 2022
72022
Cardiac ryanodine receptor N-terminal region biosensors identify novel inhibitors via FRET-based high-throughput screening
J Zhang, DP Singh, CY Ko, R Nikolaienko, SMWK Yuen, JA Schwarz, ...
Journal of Biological Chemistry 298 (1), 2022
62022
CaMKIIδ post-translational modifications increase affinity for calmodulin inside cardiac ventricular myocytes
M Simon, CY Ko, RT Rebbeck, S Baidar, RL Cornea, DM Bers
Journal of molecular and cellular cardiology 161, 53-61, 2021
52021
Complex early and delayed afterdepolarization dynamics caused by voltage-calcium coupling in cardiac myocytes
Z Song, CY Ko, M Nivala, JN Weiss, Z Qu
Biophysical Journal 108 (2), 261a-262a, 2015
42015
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Articles 1–20