Nasim Sabouri
Nasim Sabouri
Associate Professor, Umeå University
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Idling by DNA polymerase δ maintains a ligatable nick during lagging-strand DNA replication
P Garg, CM Stith, N Sabouri, E Johansson, PM Burgers
Genes & development 18 (22), 2764-2773, 2004
Unwinding the functions of the Pif1 family helicases
ML Bochman, N Sabouri, VA Zakian
DNA repair 9 (3), 237-249, 2010
In Vivo Occupancy of Mitochondrial Single-Stranded DNA Binding Protein Supports the Strand Displacement Mode of DNA Replication
J Miralles Fusté, Y Shi, S Wanrooij, X Zhu, E Jemt, Ö Persson, N Sabouri, ...
PLoS genetics 10 (12), e1004832, 2014
Structure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo–electron microscopy
FJ Asturias, IK Cheung, N Sabouri, O Chilkova, D Wepplo, E Johansson
Nature structural & molecular biology 13 (1), 35-43, 2006
DNA replication through hard-to-replicate sites, including both highly transcribed RNA Pol II and Pol III genes, requires the S. pombe Pfh1 helicase
N Sabouri, KR McDonald, CJ Webb, IM Cristea, VA Zakian
Genes & development 26 (6), 581-593, 2012
Evidence for lesion bypass by yeast replicative DNA polymerases during DNA damage
N Sabouri, J Viberg, DK Goyal, E Johansson, A Chabes
Nucleic acids research 36 (17), 5660-5667, 2008
The essential Schizosaccharomyces pombe Pfh1 DNA helicase promotes fork movement past G-quadruplex motifs to prevent DNA damage
N Sabouri, JA Capra, VA Zakian
BMC biology 12 (1), 1-14, 2014
G-rich telomeric and ribosomal DNA sequences from the fission yeast genome form stable G-quadruplex DNA structures in vitro and are unwound by the Pfh1 DNA …
M Wallgren, JB Mohammad, KP Yan, P Pourbozorgi-Langroudi, ...
Nucleic acids research 44 (13), 6213-6231, 2016
A Light‐up Logic Platform for Selective Recognition of Parallel G‐Quadruplex Structures via Disaggregation‐Induced Emission
M Deiana, K Chand, J Jamroskovic, I Obi, E Chorell, N Sabouri
Angewandte Chemie 132 (2), 906-912, 2020
Quinazoline ligands induce cancer cell death through selective STAT3 inhibition and G-quadruplex stabilization
J Jamroskovic, M Doimo, K Chand, I Obi, R Kumar, K Brännström, ...
Journal of the American Chemical Society 142 (6), 2876-2888, 2020
Pfh1 is an accessory replicative helicase that interacts with the replisome to facilitate fork progression and preserve genome integrity
KR McDonald, AJ Guise, P Pourbozorgi-Langroudi, IM Cristea, VA Zakian, ...
PLoS genetics 12 (9), e1006238, 2016
The Pif1 family helicase Pfh1 facilitates telomere replication and has an RPA-dependent role during telomere lengthening
KR McDonald, N Sabouri, CJ Webb, VA Zakian
DNA repair 24, 80-86, 2014
Identification of Compounds that Selectively Stabilize Specific G‐Quadruplex Structures by Using a Thioflavin T‐Displacement Assay as a Tool
J Jamroskovic, M Livendahl, J Eriksson, E Chorell, N Sabouri
Chemistry–A European Journal 22 (52), 18932-18943, 2016
Translesion synthesis of abasic sites by yeast DNA polymerase ϵ
N Sabouri, E Johansson
Journal of Biological Chemistry 284 (46), 31555-31563, 2009
The Pif1 signature motif of Pfh1 is necessary for both protein displacement and helicase unwinding activities, but is dispensable for strand-annealing activity
JB Mohammad, M Wallgren, N Sabouri
Nucleic acids research 46 (16), 8516-8531, 2018
The functions of the multi-tasking Pfh1Pif1 helicase
N Sabouri
Current genetics 63, 621-626, 2017
Identification of putative G-quadruplex DNA structures in S. pombe genome by quantitative PCR stop assay
J Jamroskovic, I Obi, A Movahedi, K Chand, E Chorell, N Sabouri
DNA repair 82, 102678, 2019
A site-specific self-assembled light-up rotor probe for selective recognition and stabilization of c-MYC G-quadruplex DNA
M Deiana, K Chand, J Jamroskovic, RN Das, I Obi, E Chorell, N Sabouri
Nanoscale 12 (24), 12950-12957, 2020
The RGG domain in the C-terminus of the DEAD box helicases Dbp2 and Ded1 is necessary for G-quadruplex destabilization
KKP Yan, I Obi, N Sabouri
Nucleic acids research 49 (14), 8339-8354, 2021
Design and Synthesis of 2, 2′‐Diindolylmethanes to Selectively Target Certain G‐Quadruplex DNA Structures
M Livendahl, J Jamroskovic, S Ivanova, P Demirel, N Sabouri, E Chorell
Chemistry–A European Journal 22 (37), 13004-13009, 2016
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